ArticleInternational journal of colorectal disease2020
The C-reactive protein to albumin ratio predicts postoperative complications in oldest-old patients with colorectal cancer.
Article in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 32 citations in OpenAlex.
- Divergent Prognostic Impact of Histopathological Features and Combined Hematological-Biochemical Indices in Rectal Versus Colorectal Cancer: A Single-Center Study.World journal of oncology · 2026Article
- Impact of the albumin-C-reactive protein-tumor marker score on postoperative prognosis in very elderly patients with colorectal cancer.Surgery today · 2026Article
- Construction of a nomogram model for postoperative complications following thoracoscopic lung cancer surgery in elderly patients: a study based on an elderly patient population.BMC geriatrics · 2026Article
- Preoperative risk stratification for postoperative inflammatory-nutritional deterioration after colorectal cancer surgery: an interpretable machine learning study.Frontiers in medicine · 2026Article
- Short- and long-term outcomes of laparoscopic right hemicolectomy with D3 resection for right colon cancer in elderly patients.Langenbeck's archives of surgery · 2024Article
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- Short-term outcomes after laparoscopic colorectal cancer surgery in patients over 90 years old: a Japanese multicenter study.BMC surgery · 2024Article
- The Role of Preoperative Inflammatory Markers in Pancreatectomy: a Norwegian Nationwide Cohort Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Predictive value of the Naples prognostic score on postoperative outcomes in patients with rectal cancer.Langenbeck's archives of surgery · 2023Article
- Efficacy of Neutrophil-to-Lymphocyte Ratio for Cancer-Specific Survival in Elderly Patients with Localized Colon Cancer: A Single Center Propensity Score-Matched Analysis.Clinical and experimental gastroenterology · 2023Article
- C-reactive protein/albumin ratio predicts survival after curative surgery in elderly patients with colorectal cancer.Updates in surgery · 2022Article
- Preoperative Serum Hypersensitive-c-Reactive-Protein (Hs-CRP) to Albumin Ratio Predicts Survival in Patients with Luminal B Subtype Breast Cancer.OncoTargets and therapy · 2021Article
- Machine Learning-based Model for Predicting Postoperative Complications among Patients with Colonic Perforation: A Retrospective study.Journal of the anus, rectum and colon · 2021Article
- Article
- Novel Model to Predict the Prognosis of Patients with Stage II-III Colon Cancer.BioMed research international · 2020Article
- Preoperative Neutrophil-BMI Ratio As a Promising New Marker for Predicting Tumor Outcomes in Colorectal Cancer.Technology in cancer research & treatmentArticle
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe C-reactive protein to albumin ratio (CAR) is a simple and useful score for predicting the outcomes of patients with various cancers. The aim of this study was to evaluate the CAR and short-term outcomes in oldest-old patients with colorectal cancer.
methodsA total of 126 patients aged 85 years and older with colorectal cancer who underwent resection for primary colon cancer from April 2015 to December 2018 were included. The preoperative cutoff value of the CAR for predicting postoperative complications was 0.19 on receiver operating characteristic curve analysis. Clinical characteristics and inflammation-based scores were compared between patients with a high CAR (CAR ≥ 0.19, n = 44) and a low CAR (CAR < 0.19, n = 82).
resultsA high preoperative CAR level (≥ 0.19) was significantly associated with stoma construction (p = 0.004), blood loss (p = 0.003), postoperative complications (p = 0.016), and systemic inflammation marker levels, including a low neutrophil to lymphocyte ratio (p = 0.006), a low platelet to lymphocyte ratio (p = 0.005), a low prognostic nutritional index (p < 0.001), and a high modified Glasgow prognostic score (p < 0.001). On univariate and multivariate analyses, only the CAR was an independent predictor of postoperative complications (HR 2.864, p = 0.029).
conclusionsA high CAR was significantly associated with postoperative complications for oldest-old patients with colorectal cancer.
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