SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Methylprednisolone pulse therapy as an adjuvant treatment of Streptococcus pneumoniae meningitis complicated by cerebral infarction-a case report and review of the literature.
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Delayed cerebral vasculopathy following pneumococcal meningitis: a case report.Oxford medical case reports · 2025Article
- Acute multiple brain infarctions associated with Streptococcus suis infection: a case report.BMC infectious diseases · 2024Article
- Effect of New Nursing on Patients with Acute Cerebral Infarction.Computational and mathematical methods in medicine · 2022Article
- Outbreak of COVID-19: An emerging global pandemic threat.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020Review
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5 authors at 1 institution in 1 country.
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Abstract
purposeThe role of methylprednisolone pulse therapy as adjuvant treatment of Streptococcus pneumoniae meningitis complicated by cerebral infarction has rarely been reported.
methodsWe reported a case report and also performed a systematic literature review.
resultsA 1-year 2-month-old boy who presented with high fever, status epilepticus, and septic shock was diagnosed with cerebral infarction caused by Streptococcus pneumoniae meningitis on magnetic resonance imaging (MRI). He was treated with methylprednisolone pulse therapy and his clinical condition gradually improved thereafter. At the follow-up visit 1 year after discharge, he was able to sit without support, but he had moderate delays in speech and developmental milestones and epilepsy sequelae.
conclusionIn severe cases, the use of high-dose methylprednisolone should be considered to modulate the inflammatory response in patients with severe cerebral infarction caused by Streptococcus pneumoniae meningitis.
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