Evidence map›Paper›PMID 31897584›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2020

Lymphoscintigraphy and sentinel lymph node biopsy in vulvar carcinoma: update from a European expert panel.

Angela Collarino, Valentina Fuoco, Giorgia Garganese, Lenka M Pereira Arias-Bouda, Germano Perotti, Gianpiero Manca, Sergi Vidal-Sicart, Francesco Giammarile, Lioe-Fee de Geus-Oei, Giovanni Scambia and 3 more

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Review
  3. The role of technetium-99m isotope in sentinel lymph node identification in gynecological cancers.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
  4. Molecular image-guided surgery in gynaecological cancer: where do we stand?European journal of nuclear medicine and molecular imaging · 2024
    Review
  5. Effect of known pathological risk factors on the incidence of metastatic lymph nodes and survival in early-stage vulvar cancer: SEER analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2024
    Article
  6. Frontiers in oncology · 2024
    Article
  7. Review
  8. Laparoscopic sentinel lymph node mapping with indocyanine green in endometrial cancer: surgeon's learning curve (cumulative sum analysis).International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Observational
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Diagnostic performance of preoperative [European journal of nuclear medicine and molecular imaging · 2021
    Article
  16. Is it time to include [European journal of nuclear medicine and molecular imaging · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 4 countries.

Angela CollarinoNuclear Medicine Unit, Department of Diagnostic Imaging, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. angela.collarino@policlinicogemelli.it.
Valentina FuocoInstitute of Nuclear Medicine, Department of Diagnostic Imaging, Università Cattolica del Sacro Cuore, Rome, Italy.
Giorgia GarganeseDepartment of Woman and Child Health and Public Health, Vul.Can MDT, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Lenka M Pereira Arias-BoudaDivision of Nuclear Medicine, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Germano PerottiNuclear Medicine Unit, Department of Diagnostic Imaging, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gianpiero MancaRegional Center of Nuclear Medicine, Hospital University of Pisa, Pisa, Italy.
Sergi Vidal-SicartNuclear Medicine Department, Hospital Clinic Barcelona, Universitat de Barcelona, Institut d'investigacions biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Francesco GiammarileNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.
Lioe-Fee de Geus-OeiDivision of Nuclear Medicine, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Giovanni ScambiaDepartment of Woman and Child Health and Public Health, Vul.Can MDT, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Alessandro GiordanoNuclear Medicine Unit, Department of Diagnostic Imaging, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Renato A Valdés-OlmosDivision of Nuclear Medicine, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Marco MaccauroDepartment of Nuclear Medicine, Fondazione IRCCS Istituto Nazionale Tumori di Milano, Milan, Italy.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · ITAlrijne Ziekenhuis · NLAzienda Ospedaliera Universitaria Pisana · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITInternational Atomic Energy Agency · ATLeiden University Medical Center · NLUniversitat de Barcelona · ESUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to update the clinical practice applications and technical procedures of sentinel lymph node (SLN) biopsy in vulvar cancer from European experts.

methodsA systematic data search using PubMed/MEDLINE database was performed up to May 29, 2019. Only original studies focused on SLN biopsy in vulvar cancer, published in the English language and with a minimum of nine patients were selected.

resultsAmong 280 citations, 65 studies fulfilled the inclusion criteria. On the basis of the published evidences and consensus of European experts, this study provides an updated overview on clinical applications and technical procedures of SLN biopsy in vulvar cancer.

conclusionsSLN biopsy is nowadays the standard treatment for well-selected women with clinically negative lymph nodes. Negative SLN is associated with a low groin recurrence rate and a good 5-year disease-specific survival rate. SLN biopsy is the most cost-effective approach than lymphadenectomy in early-stage vulvar cancer. However, future trials should focus on the safe extension of the indication of SLN biopsy in vulvar cancer. Although radiotracers and optical agents are widely used in the clinical routine, there is an increasing interest for hybrid tracers like indocyanine-

Indexed as

CarcinomaSentinel Lymph NodeVulvar NeoplasmsFemaleHumansLymphatic MetastasisLymph Node ExcisionLymph NodesLymphoscintigraphyNeoplasm Recurrence, LocalSentinel Lymph Node BiopsyLymphatic mappingSentinel lymph nodeSPECT/CTVulvar neoplasm

Identifiers

PMID31897584
OpenAlexW2997829802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.