Evidence map›Paper›PMID 31897432›Full record

ArticleScience advances2019

High-throughput evolution of near-infrared serotonin nanosensors.

Sanghwa Jeong, Darwin Yang, Abraham G Beyene, Jackson Travis Del Bonis-O'Donnell, Anneliese M M Gest, Nicole Navarro, Xiaoqi Sun, Markita P Landry

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 114 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  10. Article
  11. Review
  12. Redox dye-mediated fluorescence energy transfer of carbon nanotube-based nanosensors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. High-Throughput Approaches to Engineer Fluorescent Nanosensors.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Systematic Selection of High-Affinity ssDNA Sequences to Carbon Nanotubes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sanghwa JeongDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-3529-0346
Darwin YangDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Abraham G BeyeneDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-3896-2144
Jackson Travis Del Bonis-O'DonnellDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-9135-2102
Anneliese M M GestDepartment of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.
Nicole NavarroDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-1353-2124
Xiaoqi SunDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-1965-8967
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-5832-8522
University of California, Berkeley · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
Novel optical probe for dopamine release in neural circuitsR21EY029405 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI FELLER, MARLA, LANDRY, MARKITA · 2018 to 2019
$428k
Optical montoring of modulatory neurotransmitter levels using new infrared nanonsensorsR21DA044010 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILBRECHT, LINDA E · 2017 to 2018
$323k
Imaging presynaptic correlates of cocaine locomotor sensitization with near infrared catecholamine nanosensorsR03DA052810 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2021 to 2021
$223k
NEI NIH HHS R21 EY029405NIDA NIH HHS R03 DA052810NIDA NIH HHS R21 DA044010NIGMS NIH HHS R35 GM128922NIH HHS S10 OD018174
6 · The paper itself

Abstract

Imaging neuromodulation with synthetic probes is an emerging technology for studying neurotransmission. However, most synthetic probes are developed through conjugation of fluorescent signal transducers to preexisting recognition moieties such as antibodies or receptors. We introduce a generic platform to evolve synthetic molecular recognition on the surface of near-infrared fluorescent single-wall carbon nanotube (SWCNT) signal transducers. We demonstrate evolution of molecular recognition toward neuromodulator serotonin generated from large libraries of ~6.9 × 10

Indexed as

Infrared RaysAnimalsBase SequenceBrainDNA, Single-StrandedExtracellular SpaceLigandsMagnetic Resonance SpectroscopyMiceMice, Inbred C57BLMicroscopy, FluorescenceNanotubes, CarbonNeurotransmitter AgentsOptical ImagingPolynucleotidesSerotoninDNA, Single-StrandedLigandsNanotubes, CarbonNeurotransmitter AgentsPolynucleotidesSerotonin

Identifiers

PMID31897432
PMCPMC6920020
OpenAlexW2995991076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.