Evidence map›Paper›PMID 31897430›Full record

ArticleScience advances2019

The long noncoding RNA

S Keihani, V Kluever, S Mandad, V Bansal, R Rahman, E Fritsch, L Caldi Gomes, A Gärtner, S Kügler, H Urlaub and 4 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. LncRNANon-coding RNA · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Sex-specific role for the long noncoding RNAbioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. TDP-43 Epigenetic Facets and Their Neurodegenerative Implications.International journal of molecular sciences · 2023
    Review
  14. Article
  15. The potential role of N6-methyladenosine modification of LncRNAs in contributing to the pathogenesis of chronic glomerulonephritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

S KeihaniDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.ORCID 0000-0001-8031-2036
V KlueverDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.ORCID 0000-0002-0505-8231
S MandadDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.
V BansalInstitute of Medical Systems Biology, Center for Molecular Neurobiology (ZMNH), UKE, 20246 Hamburg, Germany.ORCID 0000-0002-0944-7226
R RahmanInstitute of Medical Systems Biology, Center for Molecular Neurobiology (ZMNH), UKE, 20246 Hamburg, Germany.
E FritschDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.ORCID 0000-0002-4207-0395
L Caldi GomesDepartment of Neurology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0003-4959-2169
A GärtnerVIB Center for the Biology of Disease and Center for Human Genetics, KU Leuven, Leuven, Belgium.ORCID 0000-0001-6189-9679
S KüglerDepartment of Neurology, University Medical Center Göttingen, 37073 Göttingen, Germany.
H UrlaubDepartment of Clinical Chemistry, University Medical Center Göttingen, 37077 Göttingen, Germany.
J D WrenDepartment of Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.ORCID 0000-0003-2776-3545
S BonnInstitute of Medical Systems Biology, Center for Molecular Neurobiology (ZMNH), UKE, 20246 Hamburg, Germany.ORCID 0000-0003-4366-5662
S O RizzoliDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.
E F FornasieroDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, 37073 Göttingen, Germany.ORCID 0000-0001-7643-4962
University of Göttingen · DEUniversitätsmedizin Göttingen · DEUniversität Hamburg · DEOklahoma Medical Research Foundation · USVIB-KU Leuven Center for Cancer Biology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored. Here, we established an integrated screening strategy to discover lncRNAs implicated in neurotransmitter and synaptic vesicle release. With this approach, we identified

Indexed as

AnimalsCell MovementDNA-Binding ProteinsHEK293 CellsHippocampusHumansMiceMice, TransgenicNeurogenesisNeuronsNeurotransmitter AgentsRatsRats, WistarRNA, Long NoncodingRNA, MessengerSynaptic VesiclesDNA-Binding ProteinsNeurotransmitter AgentsRNA, Long NoncodingRNA, MessengerTARDBP protein, humanTardbp protein, mouseTardbp protein, rat

Identifiers

PMID31897430
PMCPMC6920028
OpenAlexW2996109882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.