Evidence map›Paper›PMID 31897290›Full record

ArticleInterface focus2020

Survival dynamical systems: individual-level survival analysis from population-level epidemic models.

Wasiur R KhudaBukhsh, Boseung Choi, Eben Kenah, Grzegorz A Rempała

Abstract read
In one paragraph

Article in Interface focus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Hazard curvature makes within-host variability costly for survival.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Towards Inferring Network Properties from Epidemic Data.Bulletin of mathematical biology · 2023
    Article
  8. Projecting COVID-19 cases and hospital burden in Ohio.Journal of theoretical biology · 2023
    Article
  9. COVID-19 dynamics in an Ohio prison.Frontiers in public health · 2023
    Article
  10. Article
  11. Article
  12. Projecting COVID-19 Cases and Subsequent Hospital Burden in Ohio.medRxiv : the preprint server for health sciences · 2022
    Article
  13. Dynamic survival analysis for non-Markovian epidemic models.Journal of the Royal Society, Interface · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wasiur R KhudaBukhshMathematical Biosciences Institute, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-1803-0470
Boseung ChoiDivision of Economics and Statistics, Department of National Statistics, Korea University Sejong campus, Sejong Special Autonomous City, Republic of Korea.
Eben KenahDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-7117-7773
Grzegorz A RempałaDivision of Biostatistics, College of Public Health and Mathematical Biosciences Institute, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-6307-4555

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BEDFORD, TREVOR BC · 2014 to 2018
$12.5M
Regression, Phylogenetics, and Study Design in Infectious Disease EpidemiologyR01AI116770 · NIAID · UNIVERSITY OF FLORIDA · PI KENAH, EBEN · 2016 to 2020
$1.8M
NIAID NIH HHS R01 AI116770NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

In this paper, we show that solutions to ordinary differential equations describing the large-population limits of Markovian stochastic epidemic models can be interpreted as survival or cumulative hazard functions when analysing data on individuals sampled from the population. We refer to the individual-level survival and hazard functions derived from population-level equations as a survival dynamical system (SDS). To illustrate how population-level dynamics imply probability laws for individual-level infection and recovery times that can be used for statistical inference, we show numerical examples based on synthetic data. In these examples, we show that an SDS analysis compares favourably with a complete-data maximum-likelihood analysis. Finally, we use the SDS approach to analyse data from a 2009 influenza A(H1N1) outbreak at Washington State University.

Indexed as

dynamical systemsepidemic modelsmultiscale modelsstochastic processessurvival analysis

Identifiers

PMID31897290
PMCPMC6936005

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.