Evidence map›Paper›PMID 31897279›Full record

ArticleOrthopedic reviews2019

The influence of ABO blood group on mortality in major trauma.

Uwe Hamsen, André Nohl, Andreas Baumann, Rolf Lefering, Laila Boutakmant, Christian Waydhas, Marcel Dudda, Thomas Armin Schildhauer, Marcus Jäger, Alexander Wegner

Open access · goldAbstract read
In one paragraph

Article in Orthopedic reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
  4. ABO blood groups do not predict progression of traumatic intracranial hemorrhage.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2021
    Article
  5. Trauma-induced coagulopathy.Nature reviews. Disease primers · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Uwe HamsenDepartment of General and Trauma Surgery, BG University Hospital Bergmannsheil, Bochum.
André NohlDepartment of General and Trauma Surgery, BG Klinikum Duisburg.
Andreas BaumannDepartment of Anesthesia, Pain- and Palliative Care, BG University Hospital Bergmannsheil, Bochum.
Rolf LeferingInstitut für Forschung in der Operativen Medizin (IFOM), Universität Witten/Herdecke, Köln.
Laila BoutakmantAlfried Krupp Krankenhaus Rüttenscheid, Essen.
Christian WaydhasDepartment of General and Trauma Surgery, BG University Hospital Bergmannsheil, Bochum.
Marcel DuddaDepartment of Trauma Surgery, University Hospital Essen.
Thomas Armin SchildhauerDepartment of General and Trauma Surgery, BG University Hospital Bergmannsheil, Bochum.
Marcus JägerDepartment of Orthopaedics and Trauma Surgery, University Hospital Essen, Germany.
Alexander WegnerDepartment of Orthopaedics and Trauma Surgery, University Hospital Essen, Germany.
BG University Hospital Bergmannsheil Bochum · DEEssen University Hospital · DEAlfried Krupp Hospital · DEBG Klinikum Duisburg · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ABO blood group has a profound influence on hemostasis as it is a major determinant of plasma levels of von Willebrand Factor. In vitro studies suggest that blood group O is a risk factor for increased severe bleeding while blood group non-O is a risk factor for thromboembolic events. Yet, the impact of ABO blood group outcome after multiple trauma is unknown. Retrospective multicenter case-control study from three level-1 trauma centers in Germany from 2012-2015. Inclusion criteria were severe trauma with an Injury severity score ≥9 and admission to an intensive care unit. 1281 patients (69.5% male) were included. Mean Injury Severity Score (ISS) was 21.1±12.4; mean age was 50.2±22.4 years. Distribution of blood groups was: O: 37.4%; A: 44%, B: 12.7 and AB: 5.8%. Hospital mortality depending on blood group was 9.7 (A), 10.4 (B), 6.8 (AB) and 12.7 (O) %. Multivariant logistic regression for mortality revealed an Odds ratio of 0.79 (A), 0.60 (B) and 0.54 (AB) without statistical significance (P=0.35 (A), 0.17 (B), 0.33 (AB)). Thromboembolic events (blood group O

Indexed as

blood typecoagulationHemorrhagemultiple trauma

Identifiers

PMID31897279
PMCPMC6912131
OpenAlexW2994342810

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.