ArticleExperimental and therapeutic medicine2020
MRI and pathological features of Rathke cleft cysts in the sellar region.
Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- A Data-Driven Approach for Rathke's Cleft Cysts Management.Diagnostics (Basel, Switzerland) · 2025Article
- Comparison of clinical and radiological characteristics of inflammatory and non-inflammatory Rathke cleft cysts.Japanese journal of radiology · 2025Article
- Long-term outcome of surgically treated and conservatively managed Rathke cleft cysts.Acta neurochirurgica · 2024Article
- Vertical triband flag sign for differential diagnosis of Rathke's cleft cyst.World neurosurgery: X · 2024Article
- Clinical and imaging findings for the evaluation of large Rathke's cleft cysts and cystic craniopharyngiomas.Pituitary · 2023Article
- Clinical features and surgical outcomes of Rathke cleft cysts with suprasellar components: a single-center experience of 157 cases.Acta neurochirurgica · 2023Article
- Neoplasms and tumor-like lesions of the sellar region: imaging findings with correlation to pathology and 2021 WHO classification.Neuroradiology · 2023Review
- Endoscopic Treatment of Rathke's Cleft Cysts: The Case for Simple Fenestration.Brain sciences · 2022Article
- Typing of inflammatory lesions of the pituitary.Pituitary · 2022Article
- Diagnostic value of magnetic resonance imaging ectopic posterior pituitary hyperintense signal in pituitary macroadenoma.Frontiers in oncology · 2022Article
- MR-Based Radiomics for Differential Diagnosis between Cystic Pituitary Adenoma and Rathke Cleft Cyst.Computational and mathematical methods in medicine · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to investigate the MRI and pathological features of Rathke cleft cysts (RCC) in the sellar region. A total of 45 RCC cases were retrospectively analyzed. RCC size, location, intracyst nodules and general signals, as well as the posterior pituitary bright spot (PPBS) were analyzed using MRI-T1 weighted images (T1WI) and T2WI. The relationship between the presence of PPBS and histopathological features was additionally evaluated. On T1WI, there were 18 cases of isointense signal, 16 cases of hyperintense signal, 9 cases of hypointense signal, 1 case of heterogeneous signal and 1 case with a stratification effect, with isointense signal in the upper part and hyperintense signal in the lower part. On T2WI, there were 5 cases of isointense signal, 27 cases of hyperintense signal, 11 cases of hypointense signal and 1 case of the stratification effect. There were 10 cases of PPBS+ and 35 cases of PPBS-. There were no significant differences in the age, sex, cyst location and size between PPBS+ and PPBS- cases. However, PPBS+ cases had significantly lower inflammation than PPBS- cases. A total of 20 cases of intracystic nodules were identified on MRI scans, most of which exhibited T2 -hypointense signals. The shape of RCC nodules varied and there were 17 cases where the nodules were non-adherent to the cyst wall. The MRI signals of RCCs varied and most nodules were floating within cysts. Intracystic nodules are characteristic features of RCCs when observed by MRI and thus are of high diagnostic value. Most patients with RCC were also PPBS-, which may be associated with an increased inflammatory response.
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