Evidence map›Paper›PMID 31896937›Full record

ReviewCurrent oncology (Toronto, Ont.)2019

A primer on the genetics of medullary thyroid cancer.

V Larouche, A Akirov, C M Thomas, M K Krzyzanowska, S Ezzat

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Risk factors for cervical lymph node metastasis in the central or lateral cervical region in medullary thyroid carcinoma: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. [Hereditary neuroendocrine neoplasms].Pathologie (Heidelberg, Germany) · 2026
    Review
  3. Article
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  5. Plasma cells and plasmacytoid features in thyroid lesions.Virchows Archiv : an international journal of pathology · 2026
    Review
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  9. International medullary thyroid carcinoma grading system: an Indian tertiary care centre experience.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

V LaroucheEndocrine Oncology Site Group, Princess Margaret Cancer Centre, Toronto, ON.
A AkirovEndocrine Oncology Site Group, Princess Margaret Cancer Centre, Toronto, ON.
C M ThomasEndocrine Oncology Site Group, Princess Margaret Cancer Centre, Toronto, ON.
M K KrzyzanowskaEndocrine Oncology Site Group, Princess Margaret Cancer Centre, Toronto, ON.
S EzzatEndocrine Oncology Site Group, Princess Margaret Cancer Centre, Toronto, ON.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medullary thyroid cancer is a rare type of neuroendocrine tumour that arises from the parafollicular cells (C cells) of the thyroid gland. It accounts for 3%-5% of thyroid cancer cases. Close to 25% of cases are familial, and 75% are considered sporadic. Familial cases are associated with a germline

Indexed as

Carcinoma, NeuroendocrineGenetic Association StudiesGenetic TestingHumansMutationProto-Oncogene MasProto-Oncogene Proteins c-retThyroid NeoplasmsMAS1 protein, humanProto-Oncogene MasProto-Oncogene Proteins c-retRET protein, humanMedullary thyroid cancermultiple endocrine neoplasia type 2RETvandetanib

Identifiers

PMID31896937
PMCPMC6927790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.