Evidence map›Paper›PMID 31896931›Full record

ArticleThe journal of physical chemistry. A2003

Metal-Enhanced Fluorescence (MEF) Due to Silver Colloids on a Planar Surface: Potential Applications of Indocyanine Green to in Vivo Imaging.

Chris D Geddes, Haishi Cao, Ignacy Gryczynski, Zygmunt Gryczynski, Jiyu Fang, Joseph R Lakowicz

Abstract read
In one paragraph

Article in The journal of physical chemistry. A, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
18.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 281 citations in OpenAlex.

  1. Review
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  5. The Optimization of the One-Pot Synthesis of Au@SiOMaterials (Basel, Switzerland) · 2024
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chris D GeddesUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
Haishi CaoUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
Ignacy GryczynskiUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
Zygmunt GryczynskiUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
Jiyu FangUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
Joseph R LakowiczUniversity Maryland Baltimore, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201.
University of Maryland, Baltimore · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI CHEUNG, HERBERT C · 1993 to 2006
$7.4M
NCRR NIH HHS P41 RR008119
6 · The paper itself

Abstract

We examined the effects of metallic silver colloids on the fluorescence spectral properties of indocyanine green (ICG), which is a dye widely used for in vivo medical testing. Silver colloids from a suspension bind spontaneously to amine-coated surfaces. These colloid-coated surfaces were found to cause a 30-fold increase in the intensity of ICG, which was held close to the metal surface by adsorbed albumin. The increased intensities of ICG were also associated with decreased lifetimes and increased photostability, which are indicative of modifying the fluorophores radiative decay rate. These results suggest the use of metal colloid-enhanced ICG for applications to retinal angiography and vascular imaging and as a contrast agent for optical tomography.

Identifiers

PMID31896931
PMCPMC6939471
OpenAlexW2017295885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.