Evidence map›Paper›PMID 31896665›Full record

ArticleJournal of clinical microbiology2020

Predictors of Clostridioides difficile Infection-Related Complications and Treatment Patterns among Nucleic Acid Amplification Test-Positive/Toxin Enzyme Immunoassay-Negative Patients.

Ryan Miller, J A Morillas, Kyle D Brizendine, Thomas G Fraser

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Emergence and Spread of Clostridioides difficile Isolates With Reduced Fidaxomicin Susceptibility in an Acute Care Hospital.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  7. Article
  8. Impact of the Reverse 2-Step Algorithm forOpen forum infectious diseases · 2024
    Article
  9. Potential underreporting of treated patients using aInfection control and hospital epidemiology · 2024
    Observational
  10. Article
  11. ImprovingAntibiotics (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryan MillerDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA.
J A MorillasDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA.
Kyle D BrizendineDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA brizenk@ccf.org.ORCID 0000-0001-9862-1929
Thomas G FraserDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The addition of toxin enzyme immunoassay (EIA) to nucleic acid amplification tests, including PCR, creates challenges in the diagnosis and management of

Indexed as

AdultAgedBacterial ToxinsClostridioides difficileClostridium InfectionsFecesFemaleHumansImmunoenzyme TechniquesMaleMiddle AgedNucleic Acid Amplification TechniquesPredictive Value of TestsRetrospective StudiesTreatment OutcomeBacterial ToxinsCDIC. difficileClostridioides difficiletoxin enzyme immunoassay

Identifiers

PMID31896665
PMCPMC7041579
OpenAlexW2998495780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.