Evidence map›Paper›PMID 31896615›Full record

ArticleOccupational and environmental medicine2020

Mortality in a cohort of US firefighters from San Francisco, Chicago and Philadelphia: an update.

Lynne Pinkerton, Stephen J Bertke, James Yiin, Matthew Dahm, Travis Kubale, Thomas Hales, Mark Purdue, James J Beaumont, Robert Daniels

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06931561 (Occupational Cancer Screening in Firefighters), which is not on this map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06931561 narecruitingnot on this mapstarted 2025, after this paper: background citation

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

TypeinterventionalSponsorInova Health Care ServicesRan2025 to 2028Enrolled800ConditionsCancerArmsWhole Body MRI, Whole Body Ultrasound, MCD Assay, Occupational Exposure Questionnaire
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lynne PinkertonDivision of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.ORCID 0000-0002-8669-487X
Stephen J BertkeDivision of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
James YiinDivision of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA jyiin@cdc.gov.
Matthew DahmDivision of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Travis KubaleWorld Trade Center Health Program, National Institute for Occupational Safety and Health (NIOSH), Washington, District of Columbia, USA.
Thomas HalesDivision of Safety Research, National Institute for Occupational Safety and Health (NIOSH), Denver, Colorado, USA.
Mark PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
James J BeaumontDepartment of Public Health Sciences, University of California Davis, Davis, California, USA.
Robert DanielsEducation and Information Division, National Institute for Occupational Safety and Health (NIOSH), Cincinnati, Ohio, USA.ORCID 0000-0002-3915-7991
National Institute for Occupational Safety and Health · USNational Cancer Institute · USUniversity of California, Davis · USWorld Trade Organization · CH

Funding

Studies of Occupational CancerZIACP010120 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI LAN, QING · 2009 to 2025
$34.4M
6 · The paper itself

Abstract

objectivesTo update the mortality experience of a previously studied cohort of 29 992 US urban career firefighters compared with the US general population and examine exposure-response relationships within the cohort.

methodsVital status was updated through 2016 adding 7 years of follow-up. Cohort mortality compared with the US population was evaluated via life table analyses. Full risk-sets, matched on attained age, race, birthdate and fire department were created and analysed using the Cox proportional hazards regression to examine exposure-response associations between select mortality outcomes and exposure surrogates (exposed-days, fire-runs and fire-hours). Models were adjusted for a potential bias from healthy worker survivor effects by including a categorical variable for employment duration.

resultsCompared with the US population, mortality from all cancers, mesothelioma, non-Hodgkin's lymphoma (NHL) and cancers of the oesophagus, intestine, rectum, lung and kidney were modestly elevated. Positive exposure-response relationships were observed for deaths from lung cancer, leukaemia and chronic obstructive pulmonary disease (COPD).

conclusionsThis update confirms previous findings of excess mortality from all cancers and several site-specific cancers as well as positive exposure-response relations for lung cancer and leukaemia. New findings include excess NHL mortality compared with the general population and a positive exposure-response relationship for COPD. However, there was no evidence of an association between any quantitative exposure measure and NHL.

Indexed as

FirefightersOccupationsAdolescentAdultAgedCause of DeathChicagoCohort StudiesFemaleHumansLeukemiaLung NeoplasmsLymphoma, Non-HodgkinMaleMesotheliomaMesothelioma, Malignantcancerdose-responseepidemiologyfirefighterslongitudinal studiesmortality studies

Identifiers

PMID31896615
PMCPMC10165610
OpenAlexW2997552129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.