Evidence map›Paper›PMID 31896572›Full record

ArticleAJNR. American journal of neuroradiology2020

Structural and Volumetric Brain MRI Findings in Mild Traumatic Brain Injury.

J B Patel, S H Wilson, T R Oakes, P Santhanam, L K Weaver

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Life Events and Incident Dementia: A Prospective Study of 493,787 Individuals Over 16 Years.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

J B PatelFrom Lovelace Biomedical Research (J.B.P., T.R.O., P.S.), Albuquerque, New Mexico.ORCID 0000-0002-2343-9142
S H WilsonEmmes (S.H.W.), Rockville, Maryland.ORCID 0000-0002-3416-1780
T R OakesFrom Lovelace Biomedical Research (J.B.P., T.R.O., P.S.), Albuquerque, New Mexico.ORCID 0000-0003-2338-9568
P SanthanamFrom Lovelace Biomedical Research (J.B.P., T.R.O., P.S.), Albuquerque, New Mexico.ORCID 0000-0002-9257-2799
L K WeaverDivision of Hyperbaric Medicine (L.K.W.), Intermountain Medical Center, Murray, Utah, and Intermountain LDS Hospital, Salt Lake City, Utah lindell.weaver@imail.org.ORCID 0000-0002-0602-7859
Lovelace Respiratory Research Institute · USEmmes (United States) · USUniversity of Utah · USUniversity of Wisconsin System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRoutine MR imaging findings are frequently normal following mild traumatic brain injury and have a limited role in diagnosis and management. Advanced MR imaging can assist in detecting pathology and prognostication but is not readily available outside research settings. However, 3D isotropic sequences with ∼1-mm MATERIALS AND

methodsSeventy-one military personnel with persistent symptoms and 75 controls underwent 3T MR imaging. Three neuroradiologists interpreted the scans using common data elements. FreeSurfer was used to quantify regional gray and white matter volumes.

resultsWM hyperintensities were seen in 81% of the brain-injured group versus 60% of healthy controls. The odds of ≥1 WM hyperintensity in the brain-injured group was about 3.5 times the odds for healthy controls (95% CI, 1.58-7.72;

conclusionsWhite matter findings are nonspecific and therefore a clinical challenge. Our results suggest that prior trauma should be considered in the differential diagnosis of multifocal white matter abnormalities with a clinical history of mild traumatic brain injury, particularly when a frontal predilection is observed.

Indexed as

AdultBrainBrain ConcussionCohort StudiesFemaleGray MatterHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMilitary PersonnelWhite Matter

Identifiers

PMID31896572
PMCPMC6975320
OpenAlexW2997512322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.