Evidence map›Paper›PMID 31896569›Full record

ArticleAJNR. American journal of neuroradiology2020

Vessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya Disease.

A Kathuveetil, P N Sylaja, S Senthilvelan, C Kesavadas, M Banerjee, B Jayanand Sudhir

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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  10. Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

A KathuveetilFrom the Comprehensive Stroke Care Program (A.K., P.N.S.), Department of Neurology.ORCID 0000-0001-7605-1208
P N SylajaFrom the Comprehensive Stroke Care Program (A.K., P.N.S.), Department of Neurology sylajapn@hotmail.com.ORCID 0000-0003-4896-8275
S SenthilvelanDepartments of Radiology (S.S., K.C.) and.ORCID 0000-0003-2026-6159
C KesavadasDepartments of Radiology (S.S., K.C.) and.ORCID 0000-0003-4914-8666
M BanerjeeNeurosurgery (B.J.S.), Rajiv Gandhi Centre for Biotechnology, Trivandrum, Kerala, India.ORCID 0000-0002-0842-0398
B Jayanand SudhirSree Chitra Tirunal Institute for Medical Sciences and Technology (M.B.), Trivandrum, Kerala, India.ORCID 0000-0001-7556-7333
Comprehensive Cardiovascular · USResearch Institute of Radiology · BYRajiv Gandhi Centre for Biotechnology · INSree Chitra Thirunal Institute for Medical Sciences and Technology · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

background and purposeVery few data are available with regard to high-resolution intracranial vessel wall imaging characteristics of Moyamoya disease and their relation to ischemic stroke risk. We investigated the high resolution imaging characteristics of MMD and its correlation with recent ischemic events. MATERIALS AND

methodsPatients with Moyamoya disease confirmed by DSA, including patients after revascularization, were enrolled. All the patients underwent high-resolution intracranial vessel wall imaging. Vessel wall thickening, enhancement, and the remodeling index of the bilateral distal ICA and proximal MCA were noted. The patients were followed up at 3 months and 6 months after high-resolution intracranial vessel wall imaging and the association of ischemic events with imaging characteristics was assessed.

resultsTwenty-nine patients with Moyamoya disease were enrolled. The median age at symptom onset was 12 years (range, 1-51 years). A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 3 patients (4 lesions) showed grade II enhancement. The presence of contrast enhancement (

conclusionsHigh-resolution intracranial vessel wall imaging characteristics of concentric wall thickening and enhancement are relatively rare in our cohort of patients with Moyamoya disease. The presence of wall thickening and enhancement may predict future ischemic events in patients with Moyamoya disease.

Indexed as

AdolescentAdultCerebral Arterial DiseasesCerebral ArteriesChildChild, PreschoolFemaleHumansInfantMagnetic Resonance ImagingMaleMiddle AgedMoyamoya DiseaseStrokeYoung Adult

Identifiers

PMID31896569
PMCPMC6975326
OpenAlexW2997474768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.