Evidence map›Paper›PMID 31896548›Full record

ArticlePediatrics2020

Well-Child Care Adherence After Intrauterine Opioid Exposure.

Neera K Goyal, Jessica F Rohde, Vanessa Short, Stephen W Patrick, Diane Abatemarco, Esther K Chung

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06801080 (Well Baby, Well Family Study), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06801080 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Well Baby, Well Family Study

TypeinterventionalSponsorNaval Health Research CenterRan2022 to 2025Enrolled1,181ConditionsSocial Determinants of HealthArmsHealthySteps (https://www.zerotothree.org/our-work/healthysteps/), Treatment as Usual (TAU)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Improving health and well-being for infants with prenatal substance exposure.Current problems in pediatric and adolescent health care · 2024
    Article
  16. Review
  17. CDC Recommendations for Hepatitis C Testing Among Perinatally Exposed Infants and Children - United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Neera K GoyalDepartments of Pediatrics and neera.goyal@nemours.org.
Jessica F RohdeDepartments of Pediatrics and.
Vanessa ShortObstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Stephen W PatrickDivision of Neonatology, Departments of Pediatrics and Health Policy and Vanderbilt Center for Child Health Policy, School of Medicine, Vanderbilt University, Nashville, Tennessee; and.
Diane AbatemarcoObstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Esther K ChungDepartment of Pediatrics, School of Medicine, University of Washington and Seattle Children's Hospital, Seattle, Washington.
Thomas Jefferson University · USAlfred I. duPont Hospital for Children · USSeattle Children's Hospital · USVanderbilt Health · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFor children with intrauterine opioid exposure (IOE), well-child care (WCC) provides an important opportunity to address medical, developmental, and psychosocial needs. We evaluated WCC adherence for this population.

methodsIn this retrospective cohort study, we used PEDSnet data from a pediatric primary care network spanning 3 states from 2011 to 2016. IOE was ascertained by using physician diagnosis codes. WCC adherence in the first year was defined as a postnatal or 1-month visit and completed 2-, 4-, 6-, 9-, and 12-month visits. WCC adherence in the second year was defined as completed 15- and 18-month visits. Gaps in WCC, defined as ≥2 missed consecutive WCC visits, were also evaluated. We used multivariable regression to test the independent effect of IOE status.

resultsAmong 11 334 children, 236 (2.1%) had a diagnosis of IOE. Children with IOE had a median of 6 WCC visits (interquartile range 5-7), vs 8 (interquartile range 6-8) among children who were not exposed (

conclusionsChildren <2 years of age with IOE are less likely to adhere to recommended WCC, despite receiving on-time immunizations and lead screening. Further research should be focused on the role of WCC visits to support the complex needs of this population.

Indexed as

Opioid-Related DisordersPrenatal Exposure Delayed EffectsAppointments and SchedulesChild HealthChild Health ServicesDatabases, FactualFemaleHumansInfantOutcome Assessment, Health CarePatient CompliancePregnancyRegression AnalysisRetrospective Studies

Identifiers

PMID31896548
PMCPMC6993495
OpenAlexW2998239443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.