Evidence map›Paper›PMID 31896515›Full record

ArticleBiomaterials2020

Enzymatically crosslinked silk and silk-gelatin hydrogels with tunable gelation kinetics, mechanical properties and bioactivity for cell culture and encapsulation.

Onur Hasturk, Kathryn E Jordan, Jaewon Choi, David L Kaplan

Open access · greenAbstract read
In one paragraph

Article in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 285 citations in OpenAlex.

  1. Article
  2. Review
  3. Engineering Silk Fibroin-Based Biomaterials for Neural Repair.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Enzyme-Integrated Hydrogels for Advanced Biological Applications.Polymer science & technology (Washington, D.C.) · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
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  18. Article
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Onur HasturkDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
Kathryn E JordanDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
Jaewon ChoiDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA.
David L KaplanDepartment of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA. Electronic address: david.kaplan@tufts.edu.
Tufts University · US

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
Focal Sustained Release Chemotherapy-Loaded Biomaterials at Tumor SitesR01NS094218 · NINDS · TUFTS UNIVERSITY MEDFORD · PI CHIU, BILL, KAPLAN, DAVID L. · 2017 to 2021
$1.7M
Injectable Gels for Tissue AugmentationR01EB021264 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI HOUSE, MICHAEL DOUGLAS, KAPLAN, DAVID L. · 2016 to 2019
$1.4M
NIBIB NIH HHS P41 EB002520NIBIB NIH HHS R01 EB021264NINDS NIH HHS R01 NS094218
6 · The paper itself

Abstract

Silk fibroin (SF) was enzymatically crosslinked with tyramine-substituted silk fibroin (SF-TA) or gelatin (G-TA) to fabricate hybrid hydrogels with tunable gelation kinetics, mechanical properties and bioactivity. Horseradish peroxidase (HRP)/hydrogen peroxide (H

Indexed as

FibroinsSilkCell Culture TechniquesGelatinHumansHydrogelsHydrogen PeroxideKineticsFibroinsGelatinHydrogelsHydrogen PeroxideSilkCell encapsulationCyclic RGD peptideGelatin composite hydrogelsHRP-mediated crosslinkingSilk hydrogelsTyramine substitution

Identifiers

PMID31896515
PMCPMC7667870
OpenAlexW2998621453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.