ArticlePediatric research2020
Kidney and blood pressure abnormalities 6 years after acute kidney injury in critically ill children: a prospective cohort study.
Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 45 citations in OpenAlex.
- Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidney Injury During Membrane Oxygenation pediatric ECMO cohort.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Long-term follow-up strategies for children after severe acute kidney injury.Pediatric research · 2025Article
- Progression of acute kidney injury to chronic kidney disease: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Risk factors for adverse short-term and long-term outcomes in children with severe acute kidney injury requiring continuous kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2025Article
- Kidney and blood pressure outcomes 11 years after pediatric critical illness and longitudinal impact of AKI: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Pediatric acute kidney injury and adverse health outcomes: using a foundational framework to evaluate a causal link.Pediatric nephrology (Berlin, Germany) · 2024Review
- Long-Term Kidney Outcomes after Pediatric Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2024Article
- Advances in metabolomics profiling of pediatric kidney diseases: A review.Biomolecules & biomedicine · 2024Review
- A reappraisal of risk factors for hypertension after pediatric acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2024Observational
- Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.Pediatric nephrology (Berlin, Germany) · 2024Article
- Pediatric blood pressure category predicts longitudinal blood pressure change in adolescence and early adulthood.Pediatric research · 2023Article
- Risk factors for childhood chronic kidney disease: a population-based study.Pediatric nephrology (Berlin, Germany) · 2023Article
- Perspectives of Pediatric Nephrologists, Intensivists and Nurses Regarding AKI Management and Expected Outcomes.Canadian journal of kidney health and disease · 2023Article
- Urinary metabolomics to develop predictors for pediatric acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2022Article
- 24-Hour ambulatory blood pressure monitoring 7 years after intensive care unit admission.Pediatric nephrology (Berlin, Germany) · 2022Article
- Assessing nephrology competence in general paediatrics-A survey of general paediatricians, paediatric nephrologists, residents, and program directors.Paediatrics & child health · 2022Article
- The Causes of Acute Kidney Injury in Critically Ill Children Who Needs Renal Replacement Therapy.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2022Article
- Acute kidney injury in the pediatric intensive care unit: outpatient follow-up.Pediatric research · 2022Article
- Continuous Renal Replacement Therapy in Pediatric Patients With Acute Kidney Injury After Liver Transplantation.Frontiers in pediatrics · 2022Article
- Hypertension in Pediatric Acute Lymphoblastic Leukemia Patients: Prevalence, Impact, and Management Strategies.Integrated blood pressure control · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 2 countries.
Funding
Abstract
backgroundAcute kidney injury (AKI) in pediatric intensive care unit (PICU) children may be associated with long-term chronic kidney disease or hypertension.
objectivesTo estimate (1) prevalence of kidney abnormalities (low estimated glomerular filtration rate (eGFR) or albuminuria) and blood pressure (BP) consistent with pre-hypertension or hypertension, 6 years after PICU admission; (2) if AKI is associated with these outcomes.
methodsLongitudinal study of children admitted to two Canadian PICUs (January 2005-December 2011). Exposures (retrospective): AKI or stage 2/3 AKI (KDIGO creatinine-based definition) during PICU. Primary outcome (single visit 6 years after admission): presence of (a) low eGFR (<90 ml/min/1.73 m
resultsOf 277 children, 25% had AKI. AKI and stage 2/3 AKI were associated with 2.2- and 6.6-fold higher adjusted odds, respectively, for the 6-year outcomes. Applying new hypertension guidelines attenuated associations; stage 2/3 AKI was associated with 4.5-fold higher adjusted odds for 6-year CKD signs or ≥elevated BP.
conclusionsKidney and BP abnormalities are common 6 years after PICU admission and associated with AKI. Other risk factors must be elucidated to develop follow-up recommendations and reduce cardiovascular risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.