ArticlePloS one2020
Recognition of personality disorder and anxiety disorder comorbidity in patients treated for depression in secondary psychiatric care.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07078227 (5 Years Follow-up of the Study), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
5 Years Follow-up of the Study: "Pharmacogenetics in Depressed Patients With Specific Focus on Difficult-to-treat Depresssion, Suicide Attempt and CYP2D6"
Who cites it
10 citing papers in PubMed, 35 citations in OpenAlex.
- Impact of personality functioning and pathological traits on mental wellbeing of older patients with personality disorders.BMC psychiatry · 2022Trial
- Enhanced Bilateral Accelerated Theta Burst Stimulation for Comorbid Anxiety and Depressive Disorders: The Seville Protocol.Alpha psychiatry · 2025Article
- Relationship Between Depression and Falls Among Nursing Home Residents: Protocol for an Integrative Review.JMIR research protocols · 2023Article
- 25(OH)D levels are decreased in patients with difficult-to-treat depression.Comprehensive psychoneuroendocrinology · 2022Article
- Help-Seeking Behavior and Treatment Barriers in Anxiety Disorders: Results from a Representative German Community Survey.Community mental health journal · 2021Article
- Article
- Clinical Characteristics and Self-Harm in Forensic Psychiatric Patients.Frontiers in psychiatry · 2021Article
- Investigation of early and lifetime clinical features and comorbidities for the risk of developing treatment-resistant depression in a 13-year nationwide cohort study.BMC psychiatry · 2020Article
- Schema therapy versus cognitive behavioral therapy versus individual supportive therapy for depression in an inpatient and day clinic setting: study protocol of the OPTIMA-RCT.BMC psychiatry · 2020Article
- Recognition of anxiety disorders in children: a cross-sectional vignette-based survey among general practitioners.BMJ open · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDepression is a common illness with substantial economic consequences for society and a great burden for affected individuals. About 30% of patients with depression do not respond to repeated treatments. Psychiatric comorbidity is known to affect duration, recurrence and treatment outcome of depression. However, there is a lack of knowledge on the extent to which psychiatric comorbidity is identified in the clinical setting for depressed patients in secondary psychiatric care. Therefore, the aim of this study was to compare the agreement between traditional diagnostic assessment (TDA) and a structured and comprehensive diagnostic procedure (SCDP) for identification of personality and anxiety disorder comorbidity in depressed patients in secondary psychiatric care.
methods274 patients aged 18-77 were referred from four secondary psychiatric care clinics in Sweden during 2012-2017. ICD-10 diagnoses according to TDA (mostly unstructured by psychiatric specialist and residents in psychiatry), were retrieved from medical records and compared to diagnoses resulting from the SCDP in the study. This included the Mini International Neuropsychiatric Interview, the Structured Interview for DSM Axis II Personality Disorders and semi-structured questions on psychosocial circumstances, life-events, psychiatric symptoms, psychiatric treatments, substance use, and suicidal and self-harm behaviour. The assessment was carried out by psychiatric specialists or by residents in psychiatry with at least three years of psychiatric training.
resultsSCDP identified personality disorder comorbidity in 43% of the patients compared to 11% in TDA (p<0,0001). Anxiety disorder comorbidity was identified in 58% with SCDP compared to 12% with TDA (p<0,0001).
conclusionsImportant psychiatric comorbidity seems to be unrecognized in depressive patients when using TDA, which is routine in secondary psychiatric care. Comorbidities are better identified using the proposed model involving structured and semi-structured interviews together with clinical evaluations by clinical experts.
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