Evidence map›Paper›PMID 31895813›Full record

SynthesisMedicine2020

Uterus transplant graft's arterial atherosclerotic remodeling veracity.

Robert Novotny, Jaroslav Chlupac, Jakub Kristek, Jan Pit'ha, Roman Chmel, Eva Sticova, Libor Janousek, Jiri Fronek

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Robert NovotnyTransplant Surgery Department.
Jaroslav ChlupacTransplant Surgery Department.
Jakub KristekTransplant Surgery Department.
Jan Pit'haLaboratory for Atherosclerosis Research, Institute for Clinical and Experimental Medicine.
Roman ChmelDepartment of Obstetrics and Gynecology, Faculty Hospital Motol.
Eva SticovaDepartment of Pathology, Institute for Clinical and Experimental Medicine.
Libor JanousekTransplant Surgery Department.
Jiri FronekTransplant Surgery Department.
NHS Blood and Transplant · GBCharles University · CZInstitute for Atherosclerosis Research · RUInstitute of Clinical and Experimental Medicine · CZUniversity Hospital in Motol · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUterus transplantation is a complex, multi-step experimental procedure used for the treatment of uterus absence or uterus anomaly that prevents embryo implantation or pregnancy completion.

methodTo date, only 51 uterus transplants worldwide had been performed. When simplified, it is vascularized composite allograft transplantation. While it is still an experimental procedure with encouraging results for the future, there are still many issues that have to be clarified. The most serious complications of uterus transplantation are graft rejection or grafts vascular failure.

resultsSo far, no reference to the atherosclerotic arterial infiltration of the uterus arteries was suggested and studied as one of the main causes of graft's failure.

conclusionIn this review we summarized current knowledge and possible role of uterus arterial damage, including atherosclerotic changes on the graft's survival.

Indexed as

Uterine ArteryAtherosclerosisFemaleHumansNitric OxideTunica IntimaUterusVascularized Composite AllotransplantationVascular RemodelingNitric Oxide

Identifiers

PMID31895813
PMCPMC6946415
OpenAlexW2998035816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.