Evidence map›Paper›PMID 31895547›Full record

ArticleJournal of the American Chemical Society2020

Pathway Complexity in Fuel-Driven DNA Nanostructures with Autonomous Reconfiguration of Multiple Dynamic Steady States.

Jie Deng, Andreas Walther

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ATP-Powered Signaling Between Artificial and Living Cells.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Timed Pulses in DNA Strand Displacement Reactions.Journal of the American Chemical Society · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Regulating DNA-Hybridization Using a Chemically Fueled Reaction Cycle.Journal of the American Chemical Society · 2022
    Article
  17. Orthogonal Enzyme-Driven Timers for DNA Strand Displacement Reactions.Journal of the American Chemical Society · 2022
    Article
  18. Dissipative DNA nanotechnology.Nature chemistry · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jie DengA3BMS Lab, Institute for Macromolecular Chemistry , University of Freiburg , Stefan-Meier-Straße 31 , 79104 Freiburg , Germany.ORCID 0000-0001-9774-1240
Andreas WaltherA3BMS Lab, Institute for Macromolecular Chemistry , University of Freiburg , Stefan-Meier-Straße 31 , 79104 Freiburg , Germany.ORCID 0000-0003-2170-3306
University of Freiburg · DE

Funding

European Research Council 677960
6 · The paper itself

Abstract

We introduce pathway complexity on a multicomponent systems level in chemically fueled transient DNA polymerization systems, achieving autonomous evolution over multiple structural dynamic steady states from monomers to dimers, oligomers of dimers, and randomized polymer structures before being ultimately degraded back to monomers once the fuel is consumed. The enabling key principle is to design monomer species having kinetically selected molecular recognition in the structure-forming step and which are reconfigured in an enzymatic reaction network. This nonequilibrium systems chemistry approach to pathway complexity provides new conceptual insights into fuel-driven automatons and autonomous materials design.

Indexed as

DimerizationDNAEvolution, ChemicalNanostructuresNucleic Acid ConformationPolymerizationDNA

Identifiers

PMID31895547
PMCPMC7612462
OpenAlexW2998262634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.