Evidence map›Paper›PMID 31895482›Full record

ReviewJournal of biomedical materials research. Part A2020

Current advances in biodegradable synthetic polymer based cardiac patches.

Sara McMahan, Alan Taylor, Katherine M Copeland, Zui Pan, Jun Liao, Yi Hong

Abstract readReview
In one paragraph

Review in Journal of biomedical materials research. Part A, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
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  12. Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties.International journal of molecular sciences · 2024
    Review
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  17. Article
  18. Review
  19. Article
  20. Progress in the application of patch materials in cardiovascular surgery.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara McMahanDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas.
Alan TaylorDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas.
Katherine M CopelandDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas.
Zui PanCollege of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas.
Jun LiaoDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas.
Yi HongDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas.
The University of Texas at Arlington · US

Funding

Interdisciplinary Training in Nanotechnology for Cardiovascular and Lung Diseases in North TexasT32HL134613 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG · 2017 to 2021
$1.1M
Bioactive injectable blends for cardiac stem cell recruitmentR15HL140503 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI HONG, YI · 2018 to 2018
$460k
NHLBI NIH HHS R15 HL140503NHLBI NIH HHS T32 HL134613
6 · The paper itself

Abstract

The number of people affected by heart disease such as coronary artery disease and myocardial infarction increases at an alarming rate each year. Currently, the methods to treat these diseases are restricted to lifestyle change, pharmaceuticals, and eventually heart transplant if the condition is severe enough. While these treatment options are the standard for caring for patients who suffer from heart disease, limited regenerative ability of the heart restricts the effectiveness of treatment and may lead to other heart-related health problems in the future. Because of the increasing need for more effective therapeutic technologies for treating diseased heart tissue, cardiac patches are now a large focus for researchers. The cardiac patches are designed to be integrated into the patients' natural tissue to introduce mechanical support and healing to the damaged areas. As a promising alternative, synthetic biodegradable polymer based biomaterials can be easily manipulated to customize material properties, as well as possess certain desired characteristics for cardiac patch use. This comprehensive review summarizes recent works on synthetic biodegradable cardiac patches implanted into infarcted animal models. In addition, this review describes the basic requirements that should be met for cardiac patch development, and discusses the inspirations to designing new biomaterials and technologies for cardiac patches.

Indexed as

Tissue EngineeringAnimalsBiocompatible MaterialsHumansMyocardiumPolymersTissue ScaffoldsBiocompatible MaterialsPolymersbiodegradable polymercardiac patchheart diseaseheart infarction

Identifiers

PMID31895482
PMCPMC7030941
OpenAlexW2997864129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.