Evidence map›Paper›PMID 31895235›Full record

ArticleThe Journal of bone and joint surgery. American volume2020

Selection Bias, Orthopaedic Style: Knowing What We Don't Know About Aspirin.

Vincent D Pellegrini, John Eikelboom, C McCollister Evarts, Patricia D Franklin, Samuel Z Goldhaber, Richard Iorio, Carol A Lambourne, Jay S Magaziner, Laurence S Magder, Steering Committee of The PEPPER Trial

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of bone and joint surgery. American volume, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02810704 (Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02810704 phase4completednot on this map

Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement: Balancing Safety and Effectiveness

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2016 to 2025Enrolled18,883ConditionsPulmonary Embolism, Venous ThrombosisArmsEnteric Coated Aspirin, Warfarin, Rivaroxaban
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Venous thromboembolism in orthopedic surgery: Global guidelines.Acta orthopaedica et traumatologica turcica · 2023
    Review
  4. Does aspirin prevent venous thromboembolism?Hematology. American Society of Hematology. Education Program · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vincent D PellegriniDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.ORCID 0000-0001-7492-0684
John EikelboomDivision of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-4126-1285
C McCollister EvartsDepartment of Orthopaedics, Penn State Hershey Medical Center, Hershey, Pennsylvania.ORCID 0000-0001-5079-9306
Patricia D FranklinDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-4441-0533
Samuel Z GoldhaberSection of Vascular Medicine, Department of Medicine (S.Z.G.), and Department of Orthopaedic Surgery (R.I.), Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-6450-0448
Richard IorioSection of Vascular Medicine, Department of Medicine (S.Z.G.), and Department of Orthopaedic Surgery (R.I.), Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-8083-8687
Carol A LambourneDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.ORCID 0000-0003-4939-1746
Jay S MagazinerDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-9221-5425
Laurence S MagderDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0001-9297-1952
Steering Committee of The PEPPER Trial

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
NIA NIH HHS P30 AG028747
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeSelection BiasAnticoagulantsAspirinHumansPostoperative ComplicationsVenous ThromboembolismAnticoagulantsAspirin

Identifiers

PMID31895235
PMCPMC7289131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.