Evidence map›Paper›PMID 3189513›Full record

ArticleThe American journal of pathology1988

Glial fibrillary acidic protein immunoreactivity in human respiratory tract cartilages and pulmonary chondromatous hamartomas.

G Viale, C Doglioni, P Dell'Orto, G Zanetti, P Iuzzolino, L Bontempini, G Coggi

Open access · greenAbstract read
In one paragraph

Article in The American journal of pathology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Glial fibrillary acidic protein immunoreactivity in normal and diseased human breast.Virchows Archiv. A, Pathological anatomy and histopathology · 1991
    Article
  4. Article
  5. GFAP at 50.ASN neuro
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

G VialeSecond Department of Pathology, University of Milan, School of Medicine, Milano, Italy.
C Doglioni
P Dell'Orto
G Zanetti
P Iuzzolino
L Bontempini
G Coggi
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunocytochemical investigation was performed on a large series of adult, neonatal, and fetal respiratory tract cartilages to ascertain their immunoreactivity for glial fibrillary acidic protein (GFAP) and vimentin. Two polyclonal and six different monoclonal antibodies were used to document the presence of GFAP-immunoreactive chondrocytes in all the fetal and neonatal cartilages as well as in the adult epiglottis, arythenoids, and lobar, segmental, and subsegmental bronchi. The number of chondrocytes showing GFAP immunoreactivity decreased from fetal life to adulthood. Simultaneous immunoreactivity for GFAP and vimentin has also been ascertained in chondrocytes and in perichondrial stellate or elongated cells of the 25 chondromatous hamartomas investigated. These findings document yet another "inappropriate" pattern of intermediate filament immunoreactivity in normal and neoplastic human cells, and contradict the widely held supposition that the expression of GFAP is restricted to cells of glial origin.

Indexed as

AdultCartilageFemaleFetusGlial Fibrillary Acidic ProteinHamartomaHumansImmunohistochemistryLung NeoplasmsMaleReference ValuesRespiratory SystemGlial Fibrillary Acidic Protein

Identifiers

PMID3189513
PMCPMC1880783
OpenAlexW102885242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.