ArticleEnvironmental science & technology2020
Plasticizer Degradation by Marine Bacterial Isolates: A Proteogenomic and Metabolomic Characterization.
Article in Environmental science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 178 citations in OpenAlex.
- Marine microbiomes and their expanding role in biotechnological potential: a systematic review.Archives of microbiology · 2026Pooled it
- Food or just a free ride? A meta-analysis reveals the global diversity of the Plastisphere.The ISME journal · 2021Pooled it
- Recent Advanced Technologies for the Characterization of Xenobiotic-Degrading Microorganisms and Microbial Communities.Frontiers in bioengineering and biotechnology · 2021Pooled it
- The Biotechnological Applications of Marine Bacteria.Biology · 2026Review
- Threats and Shifts in Microbial Communities of Salars Associated With Direct Lithium Extraction and Brine Reinjection.Global challenges (Hoboken, NJ) · 2026Article
- Development of Membrane Transport-Inspired Biomimetic System to Degrade Plasticizers.Chemistry, an Asian journal · 2026Article
- Bacterial degradation of aromatic ester pollutants in agro-ecosystems: implications for bioremediation.Applied microbiology and biotechnology · 2026Review
- Role of dienelactone hydrolases in PET biodegradation by flavobacteriaApplied and environmental microbiology · 2026Article
- Relative Humidity Influences Aureobasidium pullulans Degradation of Polyester Polyurethane Foam.Environmental microbiology reports · 2026Article
- Genetically engineered organisms for sustainable bioremediation of polluted environments.Biodegradation · 2026Review
- Harnessing bacterial power and omics technologies for sustainable plastic waste biodegradation.Biodegradation · 2026Review
- Article
- Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025Review
- Polyethylene terephthalate (PET) primary degradation products affect c-di-GMP-, cAMP-signaling, and quorum sensing (QS) inMicrobiology spectrum · 2025Article
- Microbial diversity analysis of municipal solid waste landfills soils of Delhi (NCR) and plastic dump sites of Uttar Pradesh region of India and their function prediction for plastic degrading enzymes.World journal of microbiology & biotechnology · 2025Article
- Metagenomic analysis reveals the roles of Actinobacteria in plasticizer-contaminated landfills and aids in identifying key degraders.Scientific reports · 2025Article
- Computational identification of plastic-degrading enzymes in ocean microbiomes.Scientific reports · 2025Article
- The Threat of Bis(2-Ethylhexyl) Phthalate in Coastal and Marine Environments: Ecotoxicological Assays Using Tropical Species from Different Trophic Levels.International journal of environmental research and public health · 2025Article
- Algae- and bacteria-based biodegradation of phthalic acid esters towards the sustainable green solution.World journal of microbiology & biotechnology · 2025Review
- Marine outfall discharges contribute to coastal microplastic pollution and the spread of antimicrobial resistance.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many commercial plasticizers are toxic endocrine-disrupting chemicals that are added to plastics during manufacturing and may leach out once they reach the environment. Traditional phthalic acid ester plasticizers (PAEs), such as dibutyl phthalate (DBP) and bis(2-ethyl hexyl) phthalate (DEHP), are now increasingly being replaced with more environmentally friendly alternatives, such as acetyl tributyl citrate (ATBC). While the metabolic pathways for PAE degradation have been established in the terrestrial environment, to our knowledge, the mechanisms for ATBC biodegradation have not been identified previously and plasticizer degradation in the marine environment remains underexplored. From marine plastic debris, we enriched and isolated microbes able to grow using a range of plasticizers and, for the first time, identified the pathways used by two phylogenetically distinct bacteria to degrade three different plasticizers (i.e., DBP, DEHP, and ATBC) via a comprehensive proteogenomic and metabolomic approach. This integrated multi-OMIC study also revealed the different mechanisms used for ester side-chain removal from the different plasticizers (esterases and enzymes involved in the β-oxidation pathway) as well as the molecular response to deal with toxic intermediates, that is, phthalate, and the lower biodegrading potential detected for ATBC than for PAE plasticizers. This study highlights the metabolic potential that exists in the biofilms that colonize plastics-the Plastisphere-to effectively biodegrade plastic additives and flags the inherent importance of microbes in reducing plastic toxicity in the environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.