ArticleBioscience reports2020
Survival and prognostic factors of patients with esophageal fistula in advanced esophageal squamous cell carcinoma.
Article in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 39 citations in OpenAlex.
- Treatment patterns and prognostic factors of radiation-associated esophageal fistula in patients with esophageal squamous cell carcinoma: a retrospective cohort study.Journal of thoracic disease · 2026Article
- AI in esophageal cancer: advances, barriers to clinical translation, and perspectives for digital health.Journal of translational medicine · 2026Review
- Successful Staged Surgery for Esophagopulmonary Fistula with Lung Abscess During Neoadjuvant Chemoradiotherapy.Journal of clinical medicine · 2026Article
- Short‑ and long‑term prognostic factors of non‑neoplastic esophageal fistula: a retrospective study of 100 patients.BMC gastroenterology · 2026Article
- Three cases of esophagorespiratory fistula following neoadjuvant DCF therapy for resectable esophageal cancer.International cancer conference journal · 2026Article
- Efficacy and safety of radiotherapy combined with chemoimmunotherapy versus chemoimmunotherapy alone as first-line treatment for metachronous oligorecurrent esophageal squamous cell carcinoma.Frontiers in oncology · 2026Article
- Clinical insights and management outcomes of tracheoesophageal and bronchoesophageal fistulas: a 20-year case series review.Journal of cardiothoracic surgery · 2025Article
- Endoscopy esophageal mucosal circumferential resection followed by bypass surgery to treat tracheoesophageal fistula.JTCVS techniques · 2025Article
- Interpretable machine learning model for predicting anastomotic leak after esophageal cancer surgery via LightGBM.BMC cancer · 2025Article
- Article
- A retrospective cohort study on radio/chemotherapy and survival following esophageal fistula in esophageal cancer patients with prior radiotherapy.BMC cancer · 2025Article
- The first case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer: case report and literature review.Journal of cardiothoracic surgery · 2025Review
- Prediction of esophageal fistula in radiotherapy/chemoradiotherapy for patients with advanced esophageal cancer by a clinical-deep learning radiomics model : Prediction of esophageal fistula in radiotherapy/chemoradiotherapy patients.BMC medical imaging · 2024Article
- Prediction of malignant esophageal fistula in esophageal cancer using a radiomics-clinical nomogram.European journal of medical research · 2024Article
- Clinical-radiomics nomogram for the risk prediction of esophageal fistula in patients with esophageal squamous cell carcinoma treated with intensity-modulated radiation therapy or volumetric-modulated arc therapy.Journal of thoracic disease · 2024Article
- Risk Factors of Esophageal Fistula Associated with Volumetric Modulated Arc Therapy for Esophageal Squamous Cell Cancer.International journal of general medicine · 2024Article
- Efficacy and Safety of Self-Expandable Metallic Stent Placement for Malignant Esophageal Fistula.Journal of clinical medicine · 2023Article
- Chinese expert consensus on interventional diagnosis and management of acquired digestive-respiratory tract fistulas (second edition).The clinical respiratory journal · 2023Review
- Article
- Clinical characteristics and risk factors for 30-day mortality in esophageal cancer patients with upper gastrointestinal bleeding: a multicenter study.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to investigate the survival and prognostic factors of patients who were with advanced esophageal squamous cell carcinoma (ESCC) and developed an esophageal fistula. The data from 221 patients with advanced ESCC developed esophageal fistula from January 2008 to December 2017 at the Harbin Medical University Cancer Hospital was retrospectively analyzed. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated by the Cox proportional hazard models. The median survival time after a diagnosis of the esophageal fistula was calculated using the Kaplan-Meier method. We found that the pathogens infected by patients are common bacteria in nosocomial infection. Besides, the incidence rate of esophagomediastinal fistula was the highest (54.2%) in the lower third of the esophagus. Kaplan-Meier analysis revealed a median survival time of 11.00 months and a median post-fistula survival time of 3.63 months in patients who developed esophageal fistula in advanced esophageal cancer. In the univariate analysis, gender, therapies for ESCC before the development of fistula, type of esophageal fistula, treatment of esophageal fistula and hemoglobin (Hb) level were the factors with significant prognostic value. Gender, type of esophageal fistula and Hb level were identified as independent prognostic factors in further multivariate analysis. In summary, our study demonstrated that several factors are significantly related to patients with esophageal fistula and should be concerned about in clinical practice.
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