Evidence map›Paper›PMID 31894452›Full record

ReviewEnvironmental geochemistry and health2020

Advance on toxicity of metal nickel nanoparticles.

Yongya Wu, Lu Kong

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental geochemistry and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Nickel carcinogenesis mechanism: cell cycle dysregulation.Environmental science and pollution research international · 2021
    Review
  19. Ni and TiOEnvironmental science and pollution research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yongya WuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.ORCID http://orcid.org/0000-0003-1135-6988
Lu KongKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. konglu_yaoyu@126.com.

Funding

National Natural Science Foundation 81502783
6 · The paper itself

Abstract

As a kind of conventional metal nanomaterial, nickel nanoparticles (Ni NPs) have broad application prospects in the fields of magnetism, energy technology and biomedicine and have quickly attracted great interest. The potential negative effects of Ni NPs have also attracted wide attention from some researchers. Studies have shown that Ni NPs cause a variety of toxic effects on cells, animals and humans and have toxic effects of multiple systems such as respiratory system, cardiovascular system and reproductive system. Ni NPs can lead to oxidative stress, apoptosis, DNA damage and inflammation and induce the increase of intracellular reactive oxygen species. The toxicity of Ni NPs is also found to be related to the mitogen-activated protein kinase pathway and the hypoxia inducible factor-1α pathway. Therefore, the toxicity and mechanism of Ni NPs are reviewed in this paper, and the future researches in this field are also proposed.

Indexed as

AnimalsApoptosisDNA DamageHumansMetal NanoparticlesNickelOxidative StressReactive Oxygen SpeciesNickelReactive Oxygen SpeciesApoptosisNickel nanoparticlesOxidative stressROSToxicity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.