ArticleJapanese journal of radiology2020
The impact of iterative reconstruction protocol, signal-to-background ratio and background activity on measurement of PET spatial resolution.
Article in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 8 citations in OpenAlex.
- Development and Initial Evaluation of 3D-printed High Resolution Brain Phantom for PET.IEEE transactions on radiation and plasma medical sciences · 2025Article
- Impact of Region-of-Interest Delineation on Stability and Reproducibility of Liver SNR Measurements inWorld journal of nuclear medicine · 2023Article
- Initial Experience withDiagnostics (Basel, Switzerland) · 2021Article
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7 authors at 3 institutions in 2 countries.
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Abstract
objectivesThe present study aims to assess the impact of acquisition time, different iterative reconstruction protocols as well as image context (including contrast levels and background activities) on the measured spatial resolution in PET images.
methodsDiscovery 690 PET/CT scanner was used to quantify spatial resolutions in terms of full width half maximum (FWHM) as derived (i) directly from capillary tubes embedded in air and (ii) indirectly from 10 mm-diameter sphere of the NEMA phantom. Different signal-to-background ratios (SBRs), background activity levels and acquisition times were applied. The emission data were reconstructed using iterative reconstruction protocols. Various combinations of iterations and subsets (it × sub) were evaluated.
resultsFor capillary tubes, improved FWHM values were obtained for higher it × sub, with improved performance for PSF algorithms relative to non-PSF algorithms. For the NEMA phantom, by increasing acquisition times from 1 to 5 min, intrinsic FWHM for reconstructions with it × sub 32 (54) was improved by 15.3% (13.2%), 15.1% (13.8%), 14.5% (12.8%) and 13.7% (12.7%) for OSEM, OSEM + PSF, OSEM + TOF and OSEM + PSF + TOF, respectively. Furthermore, for all reconstruction protocols, the FWHM improved with more impact for higher it × sub.
conclusionOur results indicate that PET spatial resolution is greatly affected by SBR, background activity and the choice of the reconstruction protocols.
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