ArticleCurrent microbiology2020
Characterization of New Fengycin Cyclic Lipopeptide Variants Produced by Bacillus amyloliquefaciens (ET) Originating from a Salt Lake of Eastern Algeria.
Article in Current microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 32 citations in OpenAlex.
- Genomic and Functional Characterization of Bacillus amyloliquefaciens H6: A Potent Fengycin-Producing Biocontrol Agent Against Fusarium graminearum.Probiotics and antimicrobial proteins · 2026Article
- Bacillus paralicheniformis strain H12 from saline soil for the management of gray mold in cherry tomatoes.World journal of microbiology & biotechnology · 2025Article
- Broad antibiosis activity ofFrontiers in microbiology · 2025Article
- Prospection for potential new non-ribosomal peptide gene clusters inFrontiers in microbiology · 2025Article
- Mechanisms and Impact of Rhizosphere Microbial Metabolites on Crop Health, Traits, Functional Components: A Comprehensive Review.Molecules (Basel, Switzerland) · 2024Review
- Screening of Antagonistic Bacteria against Three Aquatic Pathogens and Characterization of Lipopeptides inJournal of microbiology and biotechnology · 2024Article
- An Integrated Pipeline and Overexpression of a Novel Efflux Transporter, YoeA, Significantly Increases Plipastatin Production inFoods (Basel, Switzerland) · 2024Article
- Lipopeptides from Bacillus: unveiling biotechnological prospects-sources, properties, and diverse applications.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Review
- Whole-genome sequencing and antimicrobial potential of bacteria isolated from Polish honey.Applied microbiology and biotechnology · 2023Article
- Characterization ofantifungal properties of lipopeptide-producingFrontiers in bioengineering and biotechnology · 2023Article
- Optimization and characterization of biosurfactant produced by indigenousRSC advances · 2022Article
- Bacillus sp.: A Remarkable Source of Bioactive Lipopeptides.Advances in biochemical engineering/biotechnology · 2022Article
- Metabolic Profiling of RhizobacteriaFrontiers in microbiology · 2021Article
- Construction and description of a constitutive plipastatin mono-producing Bacillus subtilis.Microbial cell factories · 2020Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fengycin antibiotic displays a strong antifungal activity and inhibits the growth of a wide range of plant pathogens especially filamentous fungi. The main objective of the present study is to characterize fengycin variants produced by B. amyloliquefaciens strain (ET). LC-MS analysis of fengycin extracts has shown several molecular ion peaks corresponding to conventional fengycin homologues (MH + : m/z 1463.9; 1491.9; 1506) and some new ones (MH + : m/z 1433; 1447; 1461; and 1477). Further characterization of these precursor ions was carried out by LC-MS.MS analysis. Reporter fragment ions were observed (named A and B), they correspond to the cleavage of Orn2-Tyr3 (A), Glu1-Orn2 (B), and used for identifying fengycin variants. The reporter fragment couple ions [A/B] at [m/z 966.5/1080.5] and [m/z 994.4 /1108.5] represent fengycin A and B, respectively. The diagnostic ions at ([m/z 980/1094]) may correspond to fengycin C3, D, S or B2. Interestingly, unknown diagnostic product ions at [m/z 951/1065] and [m/z 979/1093] were detected for the first time in this study which prove that they correspond to new fengycin variants, named fengycin X and fengycin Y, respectively. The fengycin X results from a substitution of the glutamine amino acid (Q), at position 8 of the fengycin A peptide part, by an isoleucine (I) or a leucine (L) residue. This mutation should be the same in fengycin Y but compared to fengycin B.
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