ArticleNature2020
Prevention of tuberculosis in macaques after intravenous BCG immunization.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 416 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
416citing papers in PubMed, 1 pooled it
30.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
416 citing papers in PubMed, 1 synthesis or guideline pooled it, 588 citations in OpenAlex.
- Development and application of the direct mycobacterial growth inhibition assay: a systematic review.Frontiers in immunology · 2024Pooled it
- Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG.Nature communications · 2025Trial
- Route of BCG administration determines success.Human vaccines & immunotherapeutics · 2026Review
- Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Host-pathogen interactions in tuberculosis: from immunological mechanisms to translational applications.Cell insight · 2026Review
- Enrichment of CD4iScience · 2026Article
- Styrene Maleic Acid Lipid Particles Prepared from Mycobacterium tuberculosis Plasma Membrane can Potentially Induce Innate and Adaptive Immune Responses in Healthy Individuals of a Tuberculosis Hyperendemic Region.Current microbiology · 2026Article
- Lung Resident T Cells Across the Spectrum of TB Infection and Disease.bioRxiv : the preprint server for biology · 2026Article
- γδ T Cells at the Crossroads of Tuberculosis and COPD: From Early Immunity to Tissue Remodeling.International journal of molecular sciences · 2026Review
- Industrial-scale mRNA expertise meets a century of tuberculosis immunology.Nature immunology · 2026Article
- Review
- Mucosal BCG Vaccination and Immune Layering: Route-Dependent Programming of Immunity at the Respiratory Interface.Vaccines · 2026Review
- The study of immunological markers in tuberculosis across animal models and its translation to human research.Lab animal · 2026Review
- Monoclonal Antibodies Targeting Bacterial Infections: A Broad Review of the Field.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026Review
- Genetically diverse CC and DO mouse models enable comprehensive assessments of novel tuberculosis vaccines.NPJ vaccines · 2026Article
- The host immune response to Mycobacterium tuberculosis determining protection or disease progression.Nature immunology · 2026Review
- HowVaccines · 2026Review
- Mtb-Specific Interferon-Gamma ELISpot Assays Have Greater Sensitivity for Detecting Mtb Infection Compared to Tuberculin Skin Test in a Cohort of Experimentally M. tuberculosis-Infected Macaques.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies.Journal of advanced research · 2026Article
- Review
356 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors at 7 institutions in 1 country.
Patricia A DarrahVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Joseph J ZeppaDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Pauline MaielloDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Joshua A HackneyVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Marc H WadsworthRagon Institute of MGH, Harvard, and MIT, Cambridge, MA, USA.
Travis K HughesRagon Institute of MGH, Harvard, and MIT, Cambridge, MA, USA.
Supriya PokkaliVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Phillip A SwansonVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Nicole L GrantDepartment of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
Mark A RodgersDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Megha KamathVaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Chelsea M CausgroveDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Dominick J LaddyAeras, Rockville, MD, USA.
Aurelio BonaviaAeras, Rockville, MD, USA.
Danilo CasimiroAeras, Rockville, MD, USA.
Philana Ling LinDepartment of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, USA.
Edwin KleinDivision of Animal Laboratory Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Alexander G WhiteDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Charles A ScangaDepartment of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Alex K ShalekRagon Institute of MGH, Harvard, and MIT, Cambridge, MA, USA.
Mario Roederer *Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
JoAnne L Flynn *Department of Microbiology and Molecular Genetics and Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Robert A Seder *Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. rseder@mail.nih.gov.
University of Pittsburgh · USNational Institutes of Health · USAeras · USNational Institute of Allergy and Infectious Diseases · USBroad Institute · USKoch Institute for Integrative Cancer Research At MITRagon Institute of MGH, MIT and Harvard · US
Funding
Flow Cytometry CoreZICAI005101 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2025
$25.7MCenter for Cell CircuitsRM1HG006193 · NHGRI · BROAD INSTITUTE, INC. · PI BLAINEY, PAUL CLARK, HACOHEN, NIR · 2016 to 2020
$14.9MDevelopment of Vaccines to Prevent TuberculosisZIAAI005136 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SEDER, ROBERT A · 2019 to 2025
$10.2MAn integrated multiplexed genomic assay for low input clinical samples1U24AI118672 · NIAID · BROAD INSTITUTE, INC. · PI SHALEK, ALEX K · 2015 to 2019
$2.0MNHGRI NIH HHS RM1 HG006193NIAID NIH HHS U24 AI118672NIH HHS 2RM1HG006193NIH HHS 5U24AI118672
Abstract
Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide
Indexed as
Administration, IntravenousAnimalsBCG VaccineCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDisease Models, AnimalMacaca mulattaTuberculosisVaccinationBCG Vaccine
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.