Evidence map›Paper›PMID 31893944›Full record

ArticleCartilage2021

Investigation of 3D-Printed Polycaprolactone-/Polyvinylpyrrolidone-Based Constructs.

Muhammet Sefa Izgordu, Evren Isa Uzgur, Songul Ulag, Ali Sahin, Betul Karademir Yilmaz, Beyhan Kilic, Nazmi Ekren, Faik Nuzhet Oktar, Oguzhan Gunduz

Open access · bronzeAbstract read
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Cartilage · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Muhammet Sefa IzgorduDepartment of Bioengineering, Faculty of Engineering, Marmara University, Istanbul, Turkey.
Evren Isa UzgurDepartment of Bioengineering, Faculty of Engineering, Marmara University, Istanbul, Turkey.
Songul UlagCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul, Turkey.
Ali SahinGenetic and Metabolic Diseases Research Center (GEMHAM), Marmara University, Istanbul, Turkey.
Betul Karademir YilmazGenetic and Metabolic Diseases Research Center (GEMHAM), Marmara University, Istanbul, Turkey.
Beyhan KilicCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul, Turkey.
Nazmi EkrenCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul, Turkey.
Faik Nuzhet OktarDepartment of Bioengineering, Faculty of Engineering, Marmara University, Istanbul, Turkey.
Oguzhan GunduzCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul, Turkey.ORCID 0000-0002-9427-7574
Marmara University · TRYıldız Technical University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to evaluate the mechanical and biological performance of cartilage-like constructs produced by 3D printing. During the investigation, poly(ε-caprolactone) (PCL) and polyvinylpyrrolidone (PVP) were used as a matrix polymer and low-molecular-weight chitosan (CS), hyaluronic acid (HA), and alginic acid sodium salt (SA) were integrated separately with the polymer matrix to fabricate the constructs. Thermal, mechanical, morphology, and chemical properties and swelling, degradation, and biocompatibility behaviors were evaluated in detail. With the addition of 3 fillers, the melting temperature of the matrix increased with the addition of fillers, and PCL/3wt.%PVP/1wt.%HA had the highest melting temperature value. Mechanical characterization results demonstrated that the printed PCL/3wt.%PVP/1wt.%CS displayed the highest compressive strength of around 9.51 MPa. The compressive strength difference between the PCL/3wt.%PVP and PCL/3wt.%PVP/1wt.%CS was 5.38 MPa. Biocompatibility properties of the constructs were tested by mitochondrial dehydrogenase activity, and

Indexed as

PovidoneTissue ScaffoldsBiocompatible MaterialsPolyestersPrinting, Three-DimensionalTissue EngineeringBiocompatible MaterialspolycaprolactonePolyestersPovidonecartilage tissue engineeringmesenchymal stem cellpolycaprolactonepolyvinylpyrrolidone

Identifiers

PMID31893944
PMCPMC8804864
OpenAlexW2996913611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.