Evidence map›Paper›PMID 31893612›Full record

ArticleJournal of microbiology and biotechnology2020

Phloretin Protects Macrophages from

Anil Chauhan, Mihee Jang, Yangmee Kim

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anil ChauhanDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Mihee JangDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Yangmee KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Konkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages are the cells of the first-line defense system, which protect the body from foreign invaders such as bacteria. However, Gram-negative bacteria have always been the major challenge for macrophages due to the presence of lipopolysaccharides on their outer cell membrane. In the present study, we evaluated the effect of phloretin, a flavonoid commonly found in apple, on the protection of macrophages from

Indexed as

Escherichia coliAnimalsInflammationMacrophagesMiceNF-kappa BNitric OxidePhloretinRAW 264.7 CellsReactive Oxygen SpeciesSignal TransductionToll-Like Receptor 4NF-kappa BNitric OxidePhloretinReactive Oxygen SpeciesTlr4 protein, mouseToll-Like Receptor 4E. coli infectioninflammationmacrophagesPhloretinTLR4 pathway

Identifiers

PMID31893612
PMCPMC9728332
OpenAlexW3004319133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.