Evidence map›Paper›PMID 31893611›Full record

ArticleJournal of microbiology and biotechnology2020

Methyl Linderone Suppresses TPA-Stimulated IL-8 and MMP-9 Expression Via the ERK/STAT3 Pathway in MCF-7 Breast Cancer Cells.

Jae-Hwan Yoon, Thu-Huyen Pham, Jintak Lee, Jiyon Lee, Hyung-Won Ryu, Sei-Ryang Oh, Jae-Wook Oh, Do-Young Yoon

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Kanakugiol, a Compound Isolated fromJournal of microbiology and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jae-Hwan YoonDepartment of Bioscience and Biotechnology, Research Institute of Bioactive-Metabolome Network, Konkuk University, Seoul 05029, Republic of Korea.
Thu-Huyen PhamDepartment of Bioscience and Biotechnology, Research Institute of Bioactive-Metabolome Network, Konkuk University, Seoul 05029, Republic of Korea.
Jintak LeeDepartment of Bioscience and Biotechnology, Research Institute of Bioactive-Metabolome Network, Konkuk University, Seoul 05029, Republic of Korea.
Jiyon LeeDepartment of Bioscience and Biotechnology, Research Institute of Bioactive-Metabolome Network, Konkuk University, Seoul 05029, Republic of Korea.
Hyung-Won RyuNatural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea.
Sei-Ryang OhNatural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Republic of Korea.
Jae-Wook OhDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Do-Young YoonDepartment of Bioscience and Biotechnology, Research Institute of Bioactive-Metabolome Network, Konkuk University, Seoul 05029, Republic of Korea.
Konkuk University · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methyl linderone (ML), a cyclo-pentenedione, was isolated from the fruit of

Indexed as

AlkenesBreast NeoplasmsCell MovementCyclopentanesExtracellular Signal-Regulated MAP KinasesHumansInterleukin-8MAP Kinase Signaling SystemMatrix Metalloproteinase 9MCF-7 CellsPhthalic AcidsSTAT3 Transcription FactorAlkenesCXCL8 protein, humanCyclopentanesExtracellular Signal-Regulated MAP KinasesInterleukin-8Matrix Metalloproteinase 9methyllinderoneMMP9 protein, humanPhthalic AcidsSTAT3 protein, humanSTAT3 Transcription Factorterephthalic acidIL-8MCF-7 cellsmetastasisMethyl linderoneMMP-9

Identifiers

PMID31893611
PMCPMC9728293
OpenAlexW3013204031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.