Evidence map›Paper›PMID 31893365›Full record

ArticleEnvironmental science and pollution research international2020

Radical scavenging and antiproliferative effect of novel phenolic derivatives isolated from Nerium indicum against human breast cancer cell line (MCF-7)-an in silico and in vitro approach.

Thangakumar Arunachalam, Syed Zameer Ahmed Khader, Sidhra Syed Zameer Ahmed, Manimaran Vetrivel, Syed Tajudeen Syed Ameen, Ibrahim Sheriff Ameer Khadharu, Puniethaa Prabhu, Philp Robinson Jayachandran, Dastageer M Sabu

Erratum issuedAbstract read
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In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Thangakumar ArunachalamDepartment of Chemistry, C. Abdul Hakeem College, Melvisharam, Vellore, Tamil Nadu, India.
Syed Zameer Ahmed KhaderDepartment of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode, Tamil Nadu, India. zameerkhader@gmail.com.
Sidhra Syed Zameer AhmedDepartment of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode, Tamil Nadu, India.
Manimaran VetrivelDepartment of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode, Tamil Nadu, India.
Syed Tajudeen Syed AmeenDepartment of Chemistry, C. Abdul Hakeem College, Melvisharam, Vellore, Tamil Nadu, India.
Ibrahim Sheriff Ameer KhadharuDepartment of Chemistry, C. Abdul Hakeem College, Melvisharam, Vellore, Tamil Nadu, India.
Puniethaa PrabhuDepartment of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode, Tamil Nadu, India.
Philp Robinson JayachandranDepartment of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode, Tamil Nadu, India.
Dastageer M SabuDepartment of Chemistry, C. Abdul Hakeem College, Melvisharam, Vellore, Tamil Nadu, India.
Department of Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple drug resistance and increased side effects due to allopathic drugs has warned scientific community with a global alarm to identify molecules from natural sources to combat diseases with minimum or no side effects. The present investigation was aimed to identify and isolate secondary metabolites from traditionally used Nerium indicum using conventional column chromatography which led to the isolation of two compounds, C-I (fractions NB4f1) and C-II (fractions NC13b1). Further characterized, it is elucidated using spectral data and identified as N-(4-hydroxy-phenyl)-2-methoxy-2-phenyl-acetamide, molecular formula C

Indexed as

NeriumAntineoplastic AgentsApoptosisBreast NeoplasmsCell ProliferationHumansMCF-7 CellsPhenolsAntineoplastic AgentsPhenolsAnticancer.CharacterizationIn silicoMTTProliferationPurification

Identifiers

PMID31893365
OpenAlexW2998376682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.