Evidence map›Paper›PMID 31892995›Full record

ArticleGenes and environment : the official journal of the Japanese Environmental Mutagen Society2019

Assessing the endocrine disrupting potentials and genotoxicity in environmental samples from Taiwanese rivers.

Pei-Hsin Chou, Chien-Hsun Chen, Kuang-Yu Chen, Fung-Chi Ko, Tsung-Ya Tsai, Yi-Po Yeh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pei-Hsin Chou1Department of Environmental Engineering, National Cheng Kung University, 1, University Road, Tainan, 701 Taiwan.ORCID 0000-0002-9116-5139
Chien-Hsun Chen1Department of Environmental Engineering, National Cheng Kung University, 1, University Road, Tainan, 701 Taiwan.
Kuang-Yu Chen1Department of Environmental Engineering, National Cheng Kung University, 1, University Road, Tainan, 701 Taiwan.
Fung-Chi Ko2Graduate Institute of Marine Biology, National Dong Hwa University, 2, Houwan Road, Pingtung, 944 Taiwan.
Tsung-Ya Tsai1Department of Environmental Engineering, National Cheng Kung University, 1, University Road, Tainan, 701 Taiwan.
Yi-Po Yeh1Department of Environmental Engineering, National Cheng Kung University, 1, University Road, Tainan, 701 Taiwan.
National Cheng Kung University · TWNational Dong Hwa University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurface waters receive a variety of organic pollutants via wastewater discharge, and sediment represents a sink for hydrophobic contaminants. In this study, we used in vitro yeast-based reporter gene assays and a

resultsAntagonist activities for androgen receptor and retinoid X receptor (RXR) were detected in river water extracts at environmentally relevant concentrations., and sediment extracts exhibited RXR agonist, RXR antagonist, and genotoxic potentials concurrently. Σ16 PAHs in fish muscles ranged from 44.9-242.4 ng g

conclusionTaiwanese river sediment samples concomitantly exhibited RXR disrupting potentials and genotoxic activities, whereas RXR agonist and antagonist activities were simultaneously detected in several dry-season sediment extracts. PAH levels in fish muscles were categorized as minimally polluted by aromatic compounds, nonetheless, the presence of methylated PAHs in muscles samples may be of concern owing to the higher toxic potentials than their parent compounds.

Indexed as

Endocrine disrupting potentialGenotoxicityPolycyclic aromatic hydrocarbonsRec-assayYeast-based reporter gene assays

Identifiers

PMID31892995
PMCPMC6937667
OpenAlexW2997636370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.