Evidence map›Paper›PMID 31892925›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2019

[Loss to follow-up in patients treated for multidrug-resistant tuberculosis in EcuadorA Perda de seguimento de pacientes tratados para tuberculose multirresistente a medicamentos no Equador].

Nelly Tatés-Ortega, Jorge Álvarez, Lucelly López, Alberto Mendoza-Ticona, Edith Alarcón-Arrascue

Open access · diamondAbstract readEnglish Abstract
In one paragraph

Article in Revista panamericana de salud publica = Pan American journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Nelly Tatés-OrtegaEstrategia Zonal de Prevención y Control de Tuberculosis Coordinación Zonal 9-Salud, Ministerio de Salud Pública del Ecuador Ecuador Estrategia Zonal de Prevención y Control de Tuberculosis. Coordinación Zonal 9-Salud. Ministerio de Salud Pública del Ecuador, Ecuador.
Jorge ÁlvarezVigilancia Epidemiológica Zonal Coordinación Zonal 9-Salud, Ministerio de Salud Pública del Ecuador Ecuador Vigilancia Epidemiológica Zonal. Coordinación Zonal 9-Salud. Ministerio de Salud Pública del Ecuador, Ecuador.
Lucelly LópezUniversidad Pontificia Bolivariana Universidad Pontificia Bolivariana Medellín Colombia Universidad Pontificia Bolivariana, Medellín, Colombia.
Alberto Mendoza-TiconaUniversidad Nacional de San Agustín Universidad Nacional de San Agustín Arequipa Perú Universidad Nacional de San Agustín, Arequipa, Perú.
Edith Alarcón-ArrascueOrganización Panamericana de la Salud Organización Panamericana de la Salud Washington D.C. Estados Unidos de América Organización Panamericana de la Salud, Washington D.C., Estados Unidos de América.
Ministerio de Salud Pública · ECNational University of Saint Augustine · PEUniversidad Pontificia Bolivariana · COWorld Health Organization Regional Office for the Americas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDetermine the incidence of loss to follow-up (LTFU) in patients treated for rifampicin-resistant tuberculosis (RR-TB) or multidrug-resistant tuberculosis (RR/MDR-TB), and the factors associated with this discharge status in Ecuador.

methodsRetrospective cohort study of patients with RR/MDR-TB who followed the World Health Organization's 18-24-month treatment regimen in 2014 and 2015, as reported by the Ministry of Health of Ecuador. The incidence of LTFU was determined, and clinical and epidemiological manifestations of cases discharged as LTFU were compared with those discharged as successfully treated. Survival was analyzed with Cox regression in order to evaluate factors associated with LTFU.

resultsOf 328 cases, 270 (82.3%) were analyzed because they had a reported discharge status. Discharge as LTFU accounted for 39.6% of cases, and as successfully treated, 50.4%. The risk factors associated with LTFU were: previous discharge as LTFU in a previous TB episode [hazard ratio (HR): 2.96 (1.53-5.73),

conclusionThe incidence of LTFU in patients with RR/MDR-TB in Ecuador is above the average for the Region of the Americas. The three identified factors support implementation of shorter regimens and patient-centered care, in line with the End TB Strategy.

Indexed as

Ecuadorlost to follow-upMultidrug-resistant tuberculosisoperations researchtherapeutics

Identifiers

PMID31892925
PMCPMC6922079
OpenAlexW2996319103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.