Evidence map›Paper›PMID 31892795›Full record

ArticleAnnals of gastroenterology

Diagnostic yield of deep biopsy via endoscopic submucosal dissection for the diagnosis of upper gastrointestinal subepithelial tumors: a systematic review and meta-analysis.

Amaninder Dhaliwal, Sindhura Kolli, Banreet Singh Dhindsa, Harmeet Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh, Douglas G Adler

Open access · diamondAbstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Amaninder DhaliwalDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha (Amaninder Dhaliwal, Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh).
Sindhura KolliDepartment of Internal Medicine, The Brooklyn Hospital Center, New York (Sindhura Kolli).
Banreet Singh DhindsaDepartment of Internal Medicine, University of Nevada Las Vegas School of Medicine (Banreet Singh Dhindsa).
Harmeet Singh MashianaDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha (Amaninder Dhaliwal, Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh).
Neil BhogalDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha (Amaninder Dhaliwal, Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh).
Ishfaq BhatDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha (Amaninder Dhaliwal, Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh).
Shailender SinghDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha (Amaninder Dhaliwal, Singh Mashiana, Neil Bhogal, Ishfaq Bhat, Shailender Singh).
Douglas G AdlerDepartment of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Douglas G. Adler), USA.
University of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventionally, endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNA)/EUS-FNB) has been used for tissue diagnosis of upper gastrointestinal (GI) subepithelial tumors (SETs). However, deep biopsy (DB) via endoscopic submucosal dissection (ESD) is emerging as an alternative technique, given the inadequate tissue sampling with EUS-FNA/EUS-FNB. Our aim was to conduct a systematic review and meta-analysis to report the overall diagnostic yield of DB via ESD for upper GI SETs.

methodsPubMed, Cochrane Library and Web of Science databases were searched to identify studies (from commencement to Oct 2017) that reported the DB via ESD technique for diagnosis of upper GI SETs. The primary outcome of interest was the method's overall diagnostic yield and the secondary outcome was to the occurrence of complications. The meta-analysis was performed using the DerSimonian and Laird random-effects model.

resultsA total of 7 studies, comprising 209 patients with a mean age of 57.3 years, were included in the final meta-analysis. The overall pooled diagnostic yield of DB via ESD for upper GI SETs was 95% (95% confidence interval [CI] 84.91-99.98, I

conclusionDB via ESD is an effective and safe procedure for diagnosing upper GI SETs. Further multicenter randomized controlled trials are needed to validate these findings.

Indexed as

Deep biopsysubepithelial tumorssubmucosal dissection

Identifiers

PMID31892795
PMCPMC6928476
OpenAlexW2921489093

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.