Evidence map›Paper›PMID 31892729›Full record

ArticleScientific reports2019

Ginsenoside Rb1 exerts antiarrhythmic effects by inhibiting I

Zhipei Liu, Lv Song, Peipei Zhang, Zhenzhen Cao, Jie Hao, Youjia Tian, Antao Luo, Peihua Zhang, Jihua Ma

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. The purified extract of steamedJournal of ginseng research · 2023
    Article
  16. Review
  17. Effects and pharmacological mechanism of Zhigancao Decoction on electrical and structural remodeling of the atrium of rabbits induced by rapid atrial pacing.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhipei LiuCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Lv SongCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Peipei ZhangCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Zhenzhen CaoCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Jie HaoCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Youjia TianCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Antao LuoCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Peihua ZhangCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China.
Jihua MaCardio-Electrophysiological Research Laboratory, Medical College of Wuhan University of Science and Technology, Wuhan, 430065, China. mjhua@wust.edu.cn.
Wuhan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenoside Rb1 exerts its pharmacological action by regulating sodium, potassium and calcium ion channels in the membranes of nerve cells. These ion channels are also present in cardiomyocytes, but no studies have been reported to date regarding the effects of Rb1 on cardiac sodium currents (I

Indexed as

Action PotentialsAnimalsAnti-Arrhythmia AgentsCalciumCalcium ChannelsGinsenosidesMyocytes, CardiacPatch-Clamp TechniquesRabbitsSodiumSodium ChannelsAnti-Arrhythmia AgentsCalciumCalcium Channelsginsenoside Rb1GinsenosidesSodiumSodium Channels

Identifiers

PMID31892729
PMCPMC6938504
OpenAlexW2997191237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.