ArticleBMJ open2019
Complications after surgery for benign prostatic enlargement: a population-based cohort study in Ontario, Canada.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Case series - Urethral-pubic symphysis leak and osteomyelitis following GreenLight™ photoselective photovaporization of the prostate.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- Opioid prescribing patterns following surgical interventions for benign prostatic hyperplasia.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Article
- A comparative study of histotripsy parameters for the treatment of fibrotic ex-vivo human benign prostatic hyperplasia tissue.Scientific reports · 2024Article
- A Comparative Study of Histotripsy Parameters for the Treatment of Fibrotic ex-vivo Human Benign Prostatic Hyperplasia Tissue.Research square · 2024Article
- The state of TURP through a historical lens.World journal of urology · 2021Article
- 360-Degree Running Suture Technique in Robotic-Assisted Surgery for Bladder Neck Contracture.CRSLS : MIS case reports from SLSArticle
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the complication rates after benign prostatic enlargement (BPE) surgery and the effects of age, comorbidity and preoperative medical therapy.
designA retrospective, population-based cohort study using linked administrative data.
settingOntario, Canada.
participants52 162 men≥66 years undergoing first BPE surgery between 1 January 2003 to 31 December 2014.
interventionMedical therapy preoperatively and surgery for BPE. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was overall 30-day postoperative complication rates. Secondary outcomes included BPE-specific event rates (bleeding, infection, obstruction, trauma) and non-BPE specific event rates (cardiovascular, pulmonary, thromboembolic and renal). Multivariable analysis examined the association between preoperative medical therapy and postoperative complication rates.
resultsThe 30-day overall complication rate after BPE surgery was 2828 events/10 000 procedures and increased annually over the study period. Receipt of preoperative α-blocker monotherapy (relative rate (RR) 1.05; 95% CI 1.00 to 1.09; p=0.033) and antithrombotic medications (RR 1.27; 95% CI 1.22 to 1.31; p<0.0001) was associated with increased complication rates. Among the ≥80-year-old group, the rate of complications increased by 39% from 2003 to 2014 (RR 1.39; 95% CI 1.21 to 1.61; p<0.0001). The mean duration of medical and conservative management increased by a mean of 2.1 years between 2007 and 2014 (p<0.0001 for trend).
conclusionsThirty-day complication rates after BPE surgery have increased annually between 2003 and 2014. Preoperative medical therapy with alpha blockers or antithrombotics was independently associated with higher rates of complications. Over this time, the duration of conservative therapy also increased.
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