Evidence map›Paper›PMID 31892537›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Crystal structure of human LDB1 in complex with SSBP2.

Hongyang Wang, Juhyun Kim, Zhizhi Wang, Xiao-Xue Yan, Ann Dean, Wenqing Xu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Article
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  9. Article
  10. Article
  11. Article
  12. Mechanisms of Interaction between Enhancers and Promoters in ThreeInternational journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Erythroid Cell Research: 3D Chromatin, Transcription Factors and Beyond.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Mechanisms of Enhancer-Promoter Interactions in Higher Eukaryotes.International journal of molecular sciences · 2021
    Review
  19. The structural biology of canonical Wnt signalling.Biochemical Society transactions · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hongyang WangNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0002-8513-263X
Juhyun KimLaboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
Zhizhi WangDepartment of Biological Structure, University of Washington School of Medicine, Seattle, WA 98195.
Xiao-Xue YanNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China; xuwq2@shanghaitech.edu.cn snow@ibp.ac.cn ann.dean@nih.gov.
Ann DeanLaboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 xuwq2@shanghaitech.edu.cn snow@ibp.ac.cn ann.dean@nih.gov.
Wenqing XuNational Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China; xuwq2@shanghaitech.edu.cn snow@ibp.ac.cn ann.dean@nih.gov.ORCID 0000-0002-2884-3101
Chinese Academy of Sciences · CNNational Institutes of Health · USUniversity of Washington · US

Funding

Epigenetic and Developmental Regulation of Mammalian GenesZIADK075033 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI DEAN, ANN · 2009 to 2025
$24.2M
6 · The paper itself

Abstract

The Lim domain binding proteins (LDB1 and LDB2 in human and Chip in

Indexed as

Protein Interaction Domains and MotifsDimerizationDNA-Binding ProteinsGene Expression RegulationHumansLIM Domain ProteinsModels, MolecularPromoter Regions, GeneticProtein BindingProtein ConformationProtein DomainsTranscription FactorsDNA-Binding ProteinsLDB1 protein, humanLIM Domain ProteinsSSBP2 protein, humanTranscription Factorscrystal structuredimerizationLIM domain binding protein 1 (LDB1)single-stranded DNA binding protein 2 (SSBP2)Wnt enhanceosome

Identifiers

PMID31892537
PMCPMC6969494
OpenAlexW2997251654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.