Evidence map›Paper›PMID 31892359›Full record

ArticleBMC pregnancy and childbirth2019

Parental attachment and depressive symptoms in pregnancies complicated by twin-twin transfusion syndrome: a cohort study.

Fiona L Mackie, Helen Pattison, Jelena Jankovic, R Katie Morris, Mark D Kilby

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Fiona L MackieCentre for Women's & Children's Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK. fionamackie@doctors.org.uk.ORCID http://orcid.org/0000-0001-8248-5811
Helen PattisonSchool of Life and Health Sciences, Aston University, Birmingham, B4 7ET, UK.
Jelena JankovicMother and Baby Unit, Barberry, Birmingham and Solihull Mental Health NHS Foundation Trust, 25 Vincent Drive, Edgbaston, Birmingham, B15 2FG, UK.
R Katie MorrisCentre for Women's & Children's Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK.
Mark D KilbyCentre for Women's & Children's Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK.
Birmingham Women’s and Children’s NHS Foundation Trust · GBAston University · GBBirmingham and Solihull Mental Health NHS Foundation Trust · GB

Funding

The Richard and Jack Wiseman Trust NA
6 · The paper itself

Abstract

backgroundTwin-twin transfusion syndrome (TTTS) is a highly morbid condition in which treatment exists, but the pregnancy remains high-risk until delivery. It may have serious sequelae, including fetal death, and in the longer term, neurodevelopmental problems. The aim of this study is to assess antenatal and postnatal parental attachment and depressive symptoms in those with pregnancies affected by TTTS.

methodsCouples attending for fetoscopic laser ablation treatment of TTTS were asked to complete Condon's Maternal/Paternal Antenatal/Postnatal Attachment Scale as appropriate, and the Edinburgh Depression Scale the day before ablation, 4 weeks post-ablation, and 6-10 weeks postnatally.

results25/27 couples completed the pre-ablation questionnaire (median gestational age 19 + 3 weeks [interquartile range 18 + 2-20 + 6]). 8/18 eligible couples returned the post-ablation questionnaire. 5/17 eligible couples returned the postnatal questionnaire. There was no significant difference in parento-fetal attachment when mothers were compared to fathers at each time point, however parento-fetal attachment did increase over time in mothers (p = 0.004), but not fathers. Mothers reported more depressive symptoms antenatally compared to fathers (p < 0.02), but there was no difference postnatally. 50% women reported Edinburgh Depression Scale scores above the cut-off (≥15) 4 weeks post-ablation. Over time maternal depressive symptoms decreased (p = 0.006), however paternal depressive symptoms remained the same.

conclusionsThis is the first attachment and depression study in a UK cohort of parents with pregnancies affected by TTTS. Although this was a small cohort and the questionnaires used had not been validated in these circumstances, the results suggest that centres caring for these couples should be aware of the risk of maternal and paternal antenatal depression, and screen and refer for additional psychological support. Further work is needed in larger cohorts.

trial registrationISRCTN 13114861 (retrospectively registered).

Indexed as

Object AttachmentAdultCohort StudiesDepressionFathersFemaleFetofetal TransfusionFetoscopyHumansMaleMothersPregnancyPregnancy ComplicationsAttachmentDepressionMaternalPaternalTTTSTwin pregnancy

Identifiers

PMID31892359
PMCPMC6938629
OpenAlexW2999217345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.