ArticleBMC pregnancy and childbirth2019
Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study.
Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05935904 (The Progression of Metabolic Syndrome Components During Pregnancy, and the Risks for Adverse Pregnancy Outcomes in Jimma Zone, Southwest Ethiopia), which is not on this map. Cited by 65 papers, 7 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Progression of Metabolic Syndrome Components During Pregnancy, and the Risks for Adverse Pregnancy Outcomes in Jimma Zone, Southwest Ethiopia: A Prospective Cohort Study.
Who cites it
65 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Differential impacts of pregnancy-induced hypertension and chronic hypertension on maternal and foetal health outcomes: a systematic review of outcomes and risk factors.Archives of gynecology and obstetrics · 2026Pooled it
- Perinatal mortality in eastern Africa: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Pooled it
- A plethora of laboratory protocols for vitamin D receptor (VDR) gene variants detection: a systematic review of associations with hypertensive disorders of pregnancy.BMC pregnancy and childbirth · 2025Pooled it
- Pooled it
- Obstetric emergencies and adverse maternal-perinatal outcomes in Ethiopia; A systematic review and meta-analysis.Frontiers in global women's health · 2022Pooled it
- The impact of pregnancy induced hypertension on low birth weight in Ethiopia: systematic review and meta-analysis.Italian journal of pediatrics · 2020Pooled it
- Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis.BMC pregnancy and childbirth · 2020Pooled it
- [Risk factors for hypoglycemia in preterm infants with a gestational age of ≤32 weeks].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Trial
- The Cerebroplacental-Renal Ratio as a Novel Doppler-Based Marker of Adverse Perinatal Outcome in Pregnancy-Induced Hypertension.Medicina (Kaunas, Lithuania) · 2026Article
- Determinants of small vulnerable newborn births in two rural community-based cohorts in India: a prospective study.The Lancet regional health. Southeast Asia · 2026Article
- Prevalence and factors associated with stillbirth in mothers delivered by cesarean section at Orotta National Referral Maternity Hospital: case-control study.BMC pregnancy and childbirth · 2025Article
- Epidemiology of perinatal asphyxia among newborns in Ethiopia: a systematic review and meta-analysis of incidence and risk factors.Maternal health, neonatology and perinatology · 2025Review
- Magnitude of Neonatal Near Miss and Associated Factors in Hospitals of South West Shoa Zone, Central Ethiopia: A Cross-Sectional Study.Health science reports · 2025Article
- Magnitude and determinants of adverse perinatal outcomes of pregnancies complicated with preeclampsia and eclampsia at a teaching hospital in the Tigray region of Ethiopia.Scientific reports · 2025Article
- Effects of antepartum hemorrhage on maternal and perinatal adverse outcomes in Northern Ethiopia: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Effect of Hypertensive Disorders of Pregnancy (HDP) on maternal and perinatal birth outcomes in Eastern Ethiopia: a prospective cohort study.BMC pregnancy and childbirth · 2025Article
- Association between triglyceride-glucose index in early pregnancy and risk of preeclampsia: a multicenter retrospective cohort study.Lipids in health and disease · 2025Article
- Prevalence, Incidence, and Temporal Trend of Hypertensive Disorders of Pregnancy and Its Association with Adverse Perinatal Outcomes in High and Low-Middle Income Countries: A Narrative Review.Iranian journal of public health · 2025Review
- Article
- Hypertension subtypes and adverse maternal and perinatal outcomes - a retrospective population-based cohort study.BMC pregnancy and childbirth · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of pregnancy-induced hypertension in Ethiopia ranges from 2.2 to 18.3%. However, so far little is known about the adverse perinatal outcomes of pregnancy-induced hypertension in Tigray regional state, Ethiopia. Therefore, the objective of this study was to assess the effect of pregnancy-induced hypertension on adverse perinatal outcomes in Tigray Regional State, Ethiopia.
methodsa prospective cohort study was conducted on a total sample of 782 pregnant women attending antenatal care in hospitals of Tigray regional state, Ethiopia. Pregnant mothers diagnosed with PIH during the data collection period in the selected hospitals were included as exposed group and normotensive women were also enrolled as a control group. This study addresses women diagnosed with preeclampsia, eclampsia and gestational hypertension between 28 and 35 weeks of gestation. Data were collected using an interviewer-administered questionnaire and review of their medical records from February 2018, to February 2019. The adverse perinatal outcome event includes low birth weight, birth asphyxia, small for gestational age, preterm delivery, admission to neonatal intensive care unit and perinatal death. A modified Poisson regression model with robust standard errors was used to analyze relative risk.
resultsIn this study, the overall incidence of adverse perinatal outcome was higher among women with pregnancy-induced hypertension than normotensive women (66.4% vs 22.2%). After adjusted for confounders women with pregnancy-induced hypertension were born babies with a higher risk of low birth weight (adjusted RR (95%CI) = 5.1(3.4,7.8)), birth asphyxia (aRR = 2.6(1.9,3.8)), small for gestational age (aRR = 3.3(2.3,4.6)), preterm delivery (aRR = 5.2(3.4,7.9)), stillbirth (aRR = 3.46(1.40,8.54)), admission to neonatal intensive care unit (aRR = 5.1(3.1,8.4)) and perinatal death (aRR = 3.6(1.8,7.4)) compared to normotensive pregnant women.
conclusionsHigher incidences of adverse perinatal outcomes occurred among women pregnancy-induced hypertension in Tigray regional state, Ethiopia. Hence, health care providers should strengthen prevention, early diagnosis and prompt management of pregnancy-induced hypertension to reduce adverse perinatal outcomes of pregnancy-induced hypertension.
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