Evidence map›Paper›PMID 31892156›Full record

ArticleJournal of clinical medicine2019

Non-SMC Condensin I Complex Subunit H (NCAPH) Is Associated with Lymphangiogenesis and Drug Resistance in Oral Squamous Cell Carcinoma.

Hiroyuki Shimomura, Tomonori Sasahira, Chie Nakashima, Miyako Kurihara-Shimomura, Tadaaki Kirita

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  11. Lymphangiogenesis in gastric cancer: function and mechanism.European journal of medical research · 2023
    Review
  12. Article
  13. Recent Advances in Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2022
    Article
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  19. Peroxidan Plays a Tumor-Promoting Role in Oral Squamous Cell Carcinoma.International journal of molecular sciences · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hiroyuki ShimomuraDepartment of Molecular Pathology, Nara Medical University, Kashihara 634-8521, Japan.
Tomonori SasahiraDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0003-1757-1275
Chie NakashimaDepartment of Molecular Pathology, Nara Medical University, Kashihara 634-8521, Japan.
Miyako Kurihara-ShimomuraDepartment of Molecular Pathology, Nara Medical University, Kashihara 634-8521, Japan.
Tadaaki KiritaDepartment of Molecular Pathology, Nara Medical University, Kashihara 634-8521, Japan.
Nara Medical University · JP

Funding

Japan Society for the Promotion of Science 17K11621Japan Society for the Promotion of Science 18K09796Japan Society for the Promotion of Science JP26462970
6 · The paper itself

Abstract

backgroundHead and neck cancer, including oral squamous cell carcinoma (OSCC), is the sixth most common malignancy. OSCC has strong invasive ability, and its malignant potential is closely associated with local expansion and lymph node metastasis. Furthermore, local or nodal recurrence worsens OSCC prognosis. In our previous cDNA microarray analysis, non-structural maintenance of chromosome (SMC) condensin I complex subunit H (

methodsIn this study, we examined NCAPH expression in OSCC and performed a functional analysis of human OSCC cells.

results

conclusionsOur present findings suggest that NCAPH is a novel diagnostic and therapeutic target in OSCC.

Indexed as

anticancer drug resistancelymphangiogenesisNCAPHoral cancerprognosis

Identifiers

PMID31892156
PMCPMC7019401
OpenAlexW2997502913

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.