Evidence map›Paper›PMID 31892132›Full record

ArticleMolecules (Basel, Switzerland)2019

β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain.

Esraa Aly, Maitham A Khajah, Willias Masocha

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Cannabinoid CBBritish journal of pharmacology · 2025
    Review
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  8. Article
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  10. Article
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  13. Article
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  15. Article
  16. Antimicrobial, Probiotic, and Immunomodulatory Potential ofAntibiotics (Basel, Switzerland) · 2024
    Article
  17. Review
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Esraa AlyDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University, Safat 13110, Kuwait.
Maitham A KhajahDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University, Safat 13110, Kuwait.
Willias MasochaDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University, Safat 13110, Kuwait.ORCID 0000-0003-3132-5935
Kuwait University · KW

Funding

College of Graduate Studies, Kuwait University YP03/18Kuwait University SRUL02/13
6 · The paper itself

Abstract

Neuropathic pain associated with nucleoside reverse transcriptase inhibitors (NRTIs), therapeutic agents for human immunodeficiency virus (HIV), responds poorly to available drugs. Smoked cannabis was reported to relieve HIV-associated neuropathic pain in clinical trials. Some constituents of cannabis (

Indexed as

AnimalsBrainDisease Models, AnimalFemaleHumansHyperalgesiaMAP Kinase Signaling SystemMiceMice, Inbred BALB CNeuralgiaPolycyclic SesquiterpenesReceptor, Cannabinoid, CB2Reverse Transcriptase InhibitorsSkinZalcitabinecaryophyllenePolycyclic SesquiterpenesReceptor, Cannabinoid, CB2Reverse Transcriptase InhibitorsZalcitabineantiretroviralCB2 receptorcytokinesddCmechanical allodynianeuropathic painnucleoside reverse transcriptase inhibitorphytocannabinoidβ-caryophyllene

Identifiers

PMID31892132
PMCPMC6983198
OpenAlexW2997743421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.