Evidence map›Paper›PMID 31892120›Full record

ArticleViruses2019

Influenza D Virus: Serological Evidence in the Italian Population from 2005 to 2017.

Claudia M Trombetta, Serena Marchi, Ilaria Manini, Otfried Kistner, Feng Li, Pietro Piu, Alessandro Manenti, Fabrizio Biuso, Chithra Sreenivasan, Julian Druce and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Efficient replication of influenza D virus in the human airway underscores zoonotic potential.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Influenza D virus infection in China, 2022-2023.Emerging microbes & infections · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Claudia M TrombettaDepartment of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0001-7229-9919
Serena MarchiDepartment of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-6817-2461
Ilaria ManiniDepartment of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-5877-3095
Otfried KistnerVisMederi srl, Strada del Petriccio e Belriguardo 35, 53100 Siena, Italy.
Feng LiDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA.
Pietro PiuVisMederi srl, Strada del Petriccio e Belriguardo 35, 53100 Siena, Italy.
Alessandro ManentiVisMederi Research srl, Strada del Petriccio e Belriguardo 35, 53100 Siena, Italy.
Fabrizio BiusoVisMederi Research srl, Strada del Petriccio e Belriguardo 35, 53100 Siena, Italy.
Chithra SreenivasanDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA.
Julian DruceVictorian Infectious Diseases Reference Laboratory, 792 Elizabeth Street, Melbourne, VIC 3000, Australia.
Emanuele MontomoliDepartment of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, 53100 Siena, Italy.
University of Siena · ITVisMederi Research · ITSouth Dakota State University · USVictorian Infectious Diseases Reference Laboratory · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza D virus is a novel influenza virus, which was first isolated from an ailing swine in 2011 and later detected in cattle, suggesting that these animals may be a primary natural reservoir. To date, few studies have been performed on human samples and there is no conclusive evidence on the ability of the virus to infect humans. The aim of this serological study was to assess the prevalence of antibodies against influenza D virus in human serum samples collected in Italy from 2005 to 2017. Serum samples were analysed by haemagglutination inhibition and virus neutralization assays. The results showed that the prevalence of antibodies against the virus increased in the human population in Italy from 2005 to 2017, with a trend characterized by a sharp increase in some years, followed by a decline in subsequent years. The virus showed the ability to infect and elicit an immune response in humans. However, prevalence peaks in humans appear to follow epidemics in animals and not to persist in the human population.

Indexed as

AdolescentAdultAgedAged, 80 and overAntibodies, ViralBiological Specimen BanksFemaleHemagglutination Inhibition TestsHumansInfluenza, HumanItalyMaleMiddle AgedNeutralization TestsPrevalenceSeroepidemiologic StudiesAntibodies, Viralhumansinfluenza D virusItalyseroprevalence

Identifiers

PMID31892120
PMCPMC7019439
OpenAlexW2996910560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.