Evidence map›Paper›PMID 31891601›Full record

ArticlePloS one2019

Evaluation of a savings-led family-based economic empowerment intervention for AIDS-affected adolescents in Uganda: A four-year follow-up on efficacy and cost-effectiveness.

Yesim Tozan, Sicong Sun, Ariadna Capasso, Julia Shu-Huah Wang, Torsten B Neilands, Ozge Sensoy Bahar, Christopher Damulira, Fred M Ssewamala

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yesim TozanCollege of Global Public Health, New York University, New York, New York, United States of America.ORCID 0000-0001-8997-8897
Sicong SunInternational Center for Child Health and Development, Brown School, Washington University in Saint Louis, Saint Louis, Missouri, United States of America.ORCID 0000-0003-4508-604X
Ariadna CapassoCollege of Global Public Health, New York University, New York, New York, United States of America.ORCID 0000-0001-5462-7800
Julia Shu-Huah WangDepartment of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China.
Torsten B NeilandsCenter for AIDS Prevention Studies, School of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
Ozge Sensoy BaharInternational Center for Child Health and Development, Brown School, Washington University in Saint Louis, Saint Louis, Missouri, United States of America.
Christopher DamuliraInternational Center for Child Health and Development, Brown School, Washington University in Saint Louis, Saint Louis, Missouri, United States of America.
Fred M SsewamalaInternational Center for Child Health and Development, Brown School, Washington University in Saint Louis, Saint Louis, Missouri, United States of America.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Bridges to the Future: Economic Empowerment for AIDS Orphaned Children in UgandaR01HD070727 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SSEWAMALA, FRED M · 2011 to 2015
$3.2M
Strengthening Child Health Research Capacity in Resource Constrained Settings: Researcher Resilience Training (RRT)R25MH118935 · NIMH · WASHINGTON UNIVERSITY · PI SEAN JOE, Mary McKernan McKay · 2018 to 2026
$1.5M
NICHD NIH HHS R01 HD070727NICHD NIH HHS R25 HD045810NIMH NIH HHS P30 MH062246NIMH NIH HHS R25 MH067127NIMH NIH HHS R25 MH118935
6 · The paper itself

Abstract

backgroundChildren who have lost a parent to HIV/AIDS, known as AIDS orphans, face multiple stressors affecting their health and development. Family economic empowerment (FEE) interventions have the potential to improve these outcomes and mitigate the risks they face. We present efficacy and cost-effectiveness analyses of the Bridges study, a savings-led FEE intervention among AIDS-orphaned adolescents in Uganda at four-year follow-up.

methodsIntent-to-treat analyses using multilevel models compared the effects of two savings-led treatment arms: Bridges (1:1 matched incentive) and BridgesPLUS (2:1 matched incentive) to a usual care control group on the following outcomes: self-rated health, sexual health, and mental health functioning. Total per-participant costs for each arm were calculated using the treatment-on-the-treated sample. Intervention effects and per-participant costs were used to calculate incremental cost-effectiveness ratios (ICERs).

findingsAmong 1,383 participants, 55% were female, 20% were double orphans. Mean age was 12 years at baseline. At 48-months, BridgesPLUS significantly improved self-rated health, (0.25, 95% CI 0.06, 0.43), HIV knowledge (0.21, 95% CI 0.01, 0.41), self-concept (0.26, 95% CI 0.09, 0.44), and self-efficacy (0.26, 95% CI 0.09, 0.43) and lowered hopelessness (-0.28, 95% CI -0.43, -0.12); whereas Bridges improved self-rated health (0.26, 95% CI 0.08, 0.43) and HIV knowledge (0.22, 95% CI 0.05, 0.39). ICERs ranged from $224 for hopelessness to $298 for HIV knowledge per 0.2 standard deviation change.

conclusionsMost intervention effects were sustained in both treatment arms at two years post-intervention. Higher matching incentives yielded a significant and lasting effect on a greater number of outcomes among adolescents compared to lower matching incentives at a similar incremental cost per unit effect. These findings contribute to the evidence supporting the incorporation of FEE interventions within national social protection frameworks.

Indexed as

Psychosocial Support SystemsAcquired Immunodeficiency SyndromeAdolescentAid to Families with Dependent ChildrenChildChild, OrphanedCost-Benefit AnalysisFemaleFollow-Up StudiesHumansMaleMental HealthMotivationSelf EfficacySocioeconomic FactorsUganda

Identifiers

PMID31891601
PMCPMC6938344

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.