Evidence map›Paper›PMID 31891500›Full record

ArticleThe Journal of organic chemistry2020

Methoxy-Substituted Nitrodibenzofuran-Based Protecting Group with an Improved Two-Photon Action Cross-Section for Thiol Protection in Solid Phase Peptide Synthesis.

Taysir K Bader, Feng Xu, Michael H Hodny, David A Blank, Mark D Distefano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taysir K BaderDepartment of Chemistry , University of Minnesota , Minneapolis , Minnesota 55455 , United States.
Feng XuDepartment of Chemistry , University of Minnesota , Minneapolis , Minnesota 55455 , United States.
Michael H HodnyDepartment of Chemistry , University of Minnesota , Minneapolis , Minnesota 55455 , United States.
David A BlankDepartment of Chemistry , University of Minnesota , Minneapolis , Minnesota 55455 , United States.ORCID 0000-0003-2582-1537
Mark D DistefanoDepartment of Chemistry , University of Minnesota , Minneapolis , Minnesota 55455 , United States.ORCID 0000-0002-2872-0259

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
Enzymatic Protein LabelingR01GM084152 · NIGMS · UNIVERSITY OF MINNESOTA · PI DISTEFANO, MARK D · 2010 to 2019
$2.6M
LIGHT ACTIVATED ANTI-CANCER DRUGSR21CA185783 · NCI · UNIVERSITY OF MINNESOTA · PI DISTEFANO, MARK D · 2014 to 2015
$338k
NCI NIH HHS P30 CA077598NCI NIH HHS R21 CA185783NIGMS NIH HHS R01 GM084152
6 · The paper itself

Abstract

Photoremovable caging groups are useful for biological applications because the deprotection process can be initiated by illumination with light without the necessity of adding additional reagents such as acids or bases that can perturb biological activity. In solid phase peptide synthesis (SPPS), the most common photoremovable group used for thiol protection is the

Indexed as

Solid-Phase Synthesis TechniquesSulfhydryl CompoundsCysteinePhotolysisPhotonsCysteineSulfhydryl Compounds

Identifiers

PMID31891500
PMCPMC7328522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.