Evidence map›Paper›PMID 31891311›Full record

ArticleJournal of behavioral addictions2019

Functional neural changes and altered cortical-subcortical connectivity associated with recovery from Internet gaming disorder.

Guang-Heng Dong, Min Wang, Jialin Zhang, Xiaoxia Du, Marc N Potenza

Open access · goldAbstract read
In one paragraph

Article in Journal of behavioral addictions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Guang-Heng DongCenter for Cognition and Brain Disorder,The Affiliated Hospital of Hangzhou Normal University, Hangzhou,China.
Min WangCenter for Cognition and Brain Disorder,The Affiliated Hospital of Hangzhou Normal University, Hangzhou,China.
Jialin ZhangDepartment of Psychology,Zhejiang Normal University, Jinhua,China.
Xiaoxia DuShanghai Key Laboratory of Magnetic Resonance,East China Normal University, Shanghai,China.
Marc N PotenzaDepartment of Psychiatry, Department of Neurobiology, and Child Study Center,Yale University School of Medicine, New Haven, CT,USA.
Affiliated Hospital of Hangzhou Normal University · CNConnecticut Mental Health Center · USEast China Normal University · CNZhejiang Normal University · CN

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

BACKGROUND AND

aimsAlthough studies have suggested that individuals with Internet gaming disorder (IGD) may have impairments in cognitive functioning, the nature of the relationship is unclear given that the information is typically derived from cross-sectional studies.

methodsIndividuals with active IGD (

resultsSubjects' craving responses to gaming cues decreased significantly at 1 year relative to study onset. Decreased brain responses in the anterior cingulate cortex (ACC) and lentiform nucleus were observed at 1 year relative to onset. Significant positive correlations were observed between changes in brain activities in the lentiform nucleus and changes in self-reported cravings. Dynamic causal modeling analysis showed increased ACC-lentiform connectivity at 1 year relative to study onset.

conclusionsAfter recovery from IGD, individuals appear less sensitive to gaming cues. This recovery may involve increased ACC-related control over lentiform-related motivations in the control over cravings. The extent to which cortical control over subcortical motivations may be targeted in treatments for IGD should be examined further.

Indexed as

Brain MappingCuesInternetVideo GamesAdultBehavior, AddictiveCorpus StriatumCravingFemaleFollow-Up StudiesGyrus CinguliHumansLongitudinal StudiesMagnetic Resonance ImagingMaleYoung Adultanterior cingulate cortexcue-craving taskInternet gaming disorderlongitudinal studies

Identifiers

PMID31891311
PMCPMC7044574
OpenAlexW2998010747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.