Evidence map›Paper›PMID 31891278›Full record

ArticleThe Journal of international medical research2020

Relationships among resistin, adiponectin, and leptin and microvascular complications in patients with type 2 diabetes mellitus.

Li-Kun Wang, Hua Wang, Xue-Liang Wu, Li Shi, Rui-Min Yang, Yi-Cheng Wang

Abstract read
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Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  11. TheInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li-Kun WangDepartment of Ultrasound, First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Hua WangDepartment of Pharmacy, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Xue-Liang WuDepartment of General Surgery, First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Li ShiDepartment of Endocrinology, First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Rui-Min YangDepartment of Ultrasound, First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Yi-Cheng WangDepartment of Ultrasound, First Affiliated Hospital of Hebei North University, Zhangjiakou, China.ORCID https://orcid.org/0000-0003-2432-5128

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationships among serum resistin, adiponectin, and leptin and microvascular complications in patients with type 2 diabetes mellitus (T2DM).

methodsA total of 120 patients with T2DM were divided into non-microangiopathy and microangiopathy groups. Sixty age- and sex-matched healthy subjects were used as a normal control (NC) group. Body height, body mass, waist circumference, and blood pressure were determined, and waist/hip ratio (WHR), body mass index, blood glucose, lipids, resistin, leptin, adiponectin, free fatty acids (FFA), high-sensitivity C-reactive protein (hs-CRP), fasting insulin, hemoglobin A1c, and homeostatic model assessment of insulin resistance (HOMA-IR) were compared among the three groups.

resultsSerum levels of resistin, leptin, FFA, and hs-CRP were significantly higher and levels of adiponectin were significantly lower in patients in the non-microangiopathy (n = 60) and microangiopathy groups (n = 60) compared with the NC group (n = 60). Serum resistin and leptin levels in patients with T2DM were positively correlated with WHR, hs-CRP, FFA, HOMA-IR, and triglycerides, but negatively correlated with high-density lipoprotein-cholesterol (HDL-C). Serum adiponectin levels in patients with T2DM were negatively correlated with WHR, hs-CRP, FFA, HOMA-IR, and triglycerides, but positively correlated with HDL-C.

conclusionSerum resistin, adiponectin, and leptin levels correlate with the occurrence of T2DM and microvascular complications.

Indexed as

AdiponectinBlood GlucoseBody Mass IndexDiabetes Mellitus, Type 2HumansInsulin ResistanceLeptinResistinVascular DiseasesAdiponectinBlood GlucoseLeptinResistinadiponectindiabetic complicationleptinmicrovasculopathyResistintype-2 diabetes

Identifiers

PMID31891278
PMCPMC7607287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.