Evidence map›Paper›PMID 31891271›Full record

ArticleMolecular pharmaceutics2020

Ultrafast

Jochem Struppe, Caitlin M Quinn, Sucharita Sarkar, Angela M Gronenborn, Tatyana Polenova

Open access · greenAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. NMR crystallography reveals active-site protonation states of Toho-1 β-lactamase in complex with avibactam.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Breaking theACS measurement science au · 2026
    Article
  3. Article
  4. COThe journal of physical chemistry. B · 2025
    Article
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  8. Review
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  10. Optimisation ofPhysical chemistry chemical physics : PCCP · 2022
    Article
  11. Chemical reviews · 2022
    Review
  12. Review
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  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jochem StruppeBruker Biospin Corporation , 15 Fortune Drive , Billerica , Massachusetts 01821 , United States.ORCID 0000-0001-9001-5991
Caitlin M QuinnDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.ORCID 0000-0001-6172-7324
Sucharita SarkarDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Angela M GronenbornDepartment of Structural Biology , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania 15260 , United States.ORCID 0000-0001-9072-3525
Tatyana PolenovaDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.ORCID 0000-0002-0346-1131
University of Delaware · USUniversity of Pittsburgh · USBruker (United States) · US

Funding

Technology Development 2: MAS NMR and dynamic nuclear polarization for HIV-1 structural biologyP50AI150481 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRONENBORN, ANGELA M. · 2019 to 2021
$14.1M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
NIAID NIH HHS P50 AI150481NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

Magic angle spinning (MAS) NMR is a powerful method for the study of pharmaceutical compounds, and probes with spinning frequencies above 100 kHz enable an atomic-resolution analysis of sub-micromole quantities of fully protonated solids. Here, we present an ultrafast NMR crystallography approach for structural characterization of organic solids at MAS frequencies of 100-111 kHz. We assess the efficiency of

Indexed as

Antifungal AgentsCarbon IsotopesCrystallography, X-RayHistidineHydrogenHydrogen BondingMagnetic Resonance ImagingNitrogen IsotopesProton Magnetic Resonance SpectroscopyProtonsTriazolesAntifungal AgentsCarbon-13Carbon IsotopesHistidineHydrogenNitrogen-15Nitrogen IsotopesposaconazoleProtonsTriazolesNMR crystallographypharmaceuticalsPosaconazoleproton detectionultrafast magic angle spinning

Identifiers

PMID31891271
PMCPMC7307729
OpenAlexW2998608515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.