Evidence map›Paper›PMID 31891105›Full record

ArticleACS omega2019

Folic Acid-Functionalized, Condensed Magnetic Nanoparticles for Targeted Delivery of Doxorubicin to Tumor Cancer Cells Overexpressing the Folate Receptor.

Athina Angelopoulou, Argiris Kolokithas-Ntoukas, Christos Fytas, Konstantinos Avgoustakis

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 122 citations in OpenAlex.

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  8. Molecules (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Athina AngelopoulouDepartment of Pharmacy, School of Health Sciences and Department of Materials Science, School of Natural Sciences, University of Patras, Patras 26504, Greece.
Argiris Kolokithas-NtoukasDepartment of Pharmacy, School of Health Sciences and Department of Materials Science, School of Natural Sciences, University of Patras, Patras 26504, Greece.
Christos FytasDepartment of Pharmacy, School of Health Sciences and Department of Materials Science, School of Natural Sciences, University of Patras, Patras 26504, Greece.
Konstantinos AvgoustakisDepartment of Pharmacy, School of Health Sciences and Department of Materials Science, School of Natural Sciences, University of Patras, Patras 26504, Greece.
University of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study concerns the development of folic acid (FA)-functionalized iron oxide condensed colloidal magnetic clusters for a more selective delivery of doxorubicin (DOX) to tumor cancer cells overexpressing the folate receptor. Alginate-coated condensed magnetic nanoparticles (co-MIONs) were synthesized via an alkaline precipitation method of an iron precursor in the presence of sodium alginate. Poly(ethylene glycol) (OH-PEG-NH

Identifiers

PMID31891105
PMCPMC6933766
OpenAlexW2996058744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.